Histopathological Variants of Cutaneous Neurofibroma: A Compendious Review

The first description of histopathological variants of neurofibroma dates back to 1994. Over the years, many individual case reports elucidating unusual histologic features in neurofibroma have been added to the literature, some of which have defined criteria, with the others falling under the roof...

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Main Authors: Neha S. Nagrani, Jag Bhawan
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Dermatopathology
Subjects:
Online Access:https://www.mdpi.com/2296-3529/10/1/1
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author Neha S. Nagrani
Jag Bhawan
author_facet Neha S. Nagrani
Jag Bhawan
author_sort Neha S. Nagrani
collection DOAJ
description The first description of histopathological variants of neurofibroma dates back to 1994. Over the years, many individual case reports elucidating unusual histologic features in neurofibroma have been added to the literature, some of which have defined criteria, with the others falling under the roof of benign neural neoplasms. These unusual features, which sometimes may lead to pauses in identifying a common benign tumor such as neurofibroma. Awareness of these variants may help dermatopathologists avoid misinterpretation. Thus, this review aims to summarize all novel and unusual histopathological variants of cutaneous neurofibroma reported to date, in addition to any unusual variants that we encountered in our practice.
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spelling doaj.art-9f38d8e0c5cc458395e976f691f59c282023-03-28T13:25:59ZengMDPI AGDermatopathology2296-35292022-12-0110111910.3390/dermatopathology10010001Histopathological Variants of Cutaneous Neurofibroma: A Compendious ReviewNeha S. Nagrani0Jag Bhawan1Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118-2415, USADermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118-2415, USAThe first description of histopathological variants of neurofibroma dates back to 1994. Over the years, many individual case reports elucidating unusual histologic features in neurofibroma have been added to the literature, some of which have defined criteria, with the others falling under the roof of benign neural neoplasms. These unusual features, which sometimes may lead to pauses in identifying a common benign tumor such as neurofibroma. Awareness of these variants may help dermatopathologists avoid misinterpretation. Thus, this review aims to summarize all novel and unusual histopathological variants of cutaneous neurofibroma reported to date, in addition to any unusual variants that we encountered in our practice.https://www.mdpi.com/2296-3529/10/1/1cutaneous neurofibromahistopathological variantsclassification
spellingShingle Neha S. Nagrani
Jag Bhawan
Histopathological Variants of Cutaneous Neurofibroma: A Compendious Review
Dermatopathology
cutaneous neurofibroma
histopathological variants
classification
title Histopathological Variants of Cutaneous Neurofibroma: A Compendious Review
title_full Histopathological Variants of Cutaneous Neurofibroma: A Compendious Review
title_fullStr Histopathological Variants of Cutaneous Neurofibroma: A Compendious Review
title_full_unstemmed Histopathological Variants of Cutaneous Neurofibroma: A Compendious Review
title_short Histopathological Variants of Cutaneous Neurofibroma: A Compendious Review
title_sort histopathological variants of cutaneous neurofibroma a compendious review
topic cutaneous neurofibroma
histopathological variants
classification
url https://www.mdpi.com/2296-3529/10/1/1
work_keys_str_mv AT nehasnagrani histopathologicalvariantsofcutaneousneurofibromaacompendiousreview
AT jagbhawan histopathologicalvariantsofcutaneousneurofibromaacompendiousreview