Splenectomy for Visceral Leishmaniasis Out of an Endemic Region: A Case Report and Literature Review
Visceral leishmaniasis (also known as kala-azar) is characterized by fever, weight loss, swelling of the spleen and liver, and pancytopenia. If it is not treated, the fatality rate in developing countries can be as high as 100% within 2 years. In a high risk situation for perioperative bleeding due...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/58/2/184 |
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| author | Nebojsa Lekic Boris Tadic Vladimir Djordjevic Dragan Basaric Marjan Micev Dragica Vucelic Milica Mitrovic Nikola Grubor |
| author_facet | Nebojsa Lekic Boris Tadic Vladimir Djordjevic Dragan Basaric Marjan Micev Dragica Vucelic Milica Mitrovic Nikola Grubor |
| author_sort | Nebojsa Lekic |
| collection | DOAJ |
| description | Visceral leishmaniasis (also known as kala-azar) is characterized by fever, weight loss, swelling of the spleen and liver, and pancytopenia. If it is not treated, the fatality rate in developing countries can be as high as 100% within 2 years. In a high risk situation for perioperative bleeding due to severe thrombocytopenia/coagulopathy, we present a rare challenge for urgent splenectomy in a patient with previously undiagnosed visceral leishmaniasis. A histologic examination of the spleen revealed a visceral leishmaniasis, and the patient was successfully treated with amphotericin B. |
| first_indexed | 2024-03-09T21:29:44Z |
| format | Article |
| id | doaj.art-9f3c15d776d54070805581d23d8b8e11 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T21:29:44Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-9f3c15d776d54070805581d23d8b8e112023-11-23T20:59:17ZengMDPI AGMedicina1010-660X1648-91442022-01-0158218410.3390/medicina58020184Splenectomy for Visceral Leishmaniasis Out of an Endemic Region: A Case Report and Literature ReviewNebojsa Lekic0Boris Tadic1Vladimir Djordjevic2Dragan Basaric3Marjan Micev4Dragica Vucelic5Milica Mitrovic6Nikola Grubor7Department for HBP Surgery, University Clinical Centre of Serbia, Clinic for Digestive Surgery, Koste Todorovica Street, No. 6, 11000 Belgrade, SerbiaDepartment for HBP Surgery, University Clinical Centre of Serbia, Clinic for Digestive Surgery, Koste Todorovica Street, No. 6, 11000 Belgrade, SerbiaDepartment for HBP Surgery, University Clinical Centre of Serbia, Clinic for Digestive Surgery, Koste Todorovica Street, No. 6, 11000 Belgrade, SerbiaDepartment for HBP Surgery, University Clinical Centre of Serbia, Clinic for Digestive Surgery, Koste Todorovica Street, No. 6, 11000 Belgrade, SerbiaDepartment for Pathology, University Clinical Centre of Serbia, Clinic for Digestive Surgery, Koste Todorovica Street, No. 6, 11000 Belgrade, SerbiaDepartment of Transfusion Medicine, Faculty of Medicine, University of Belgrade, Koste Todorovica Street, No. 6, 11000 Belgrade, SerbiaCenter for Radiology and Magnetic Resonance Imaging, University Clinical Centre of Serbia, Pasterova No. 2, 11000 Belgrade, SerbiaDepartment for HBP Surgery, University Clinical Centre of Serbia, Clinic for Digestive Surgery, Koste Todorovica Street, No. 6, 11000 Belgrade, SerbiaVisceral leishmaniasis (also known as kala-azar) is characterized by fever, weight loss, swelling of the spleen and liver, and pancytopenia. If it is not treated, the fatality rate in developing countries can be as high as 100% within 2 years. In a high risk situation for perioperative bleeding due to severe thrombocytopenia/coagulopathy, we present a rare challenge for urgent splenectomy in a patient with previously undiagnosed visceral leishmaniasis. A histologic examination of the spleen revealed a visceral leishmaniasis, and the patient was successfully treated with amphotericin B.https://www.mdpi.com/1648-9144/58/2/184visceral leishmaniasisimpaired hemostasisthromboelastometrysplenectomy |
| spellingShingle | Nebojsa Lekic Boris Tadic Vladimir Djordjevic Dragan Basaric Marjan Micev Dragica Vucelic Milica Mitrovic Nikola Grubor Splenectomy for Visceral Leishmaniasis Out of an Endemic Region: A Case Report and Literature Review Medicina visceral leishmaniasis impaired hemostasis thromboelastometry splenectomy |
| title | Splenectomy for Visceral Leishmaniasis Out of an Endemic Region: A Case Report and Literature Review |
| title_full | Splenectomy for Visceral Leishmaniasis Out of an Endemic Region: A Case Report and Literature Review |
| title_fullStr | Splenectomy for Visceral Leishmaniasis Out of an Endemic Region: A Case Report and Literature Review |
| title_full_unstemmed | Splenectomy for Visceral Leishmaniasis Out of an Endemic Region: A Case Report and Literature Review |
| title_short | Splenectomy for Visceral Leishmaniasis Out of an Endemic Region: A Case Report and Literature Review |
| title_sort | splenectomy for visceral leishmaniasis out of an endemic region a case report and literature review |
| topic | visceral leishmaniasis impaired hemostasis thromboelastometry splenectomy |
| url | https://www.mdpi.com/1648-9144/58/2/184 |
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