CLINICAL EFFECT OF TESTOSTERONE IN MEN WITH STABLE ANGINA

Aim. To study efficacy of testosterone undecanoate (TU) therapy in men with stable angina and androgen deficiency.Material and methods. The serum testosterone level was detected in 247 men (aged 51,6±1,8 y.o.) with stable effort angina. 60 patients with androgen deficiency additionally to basic angi...

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Main Authors: A. Ya. Kravchenko, V. M. Provotorov
Format: Article
Language:English
Published: Столичная издательская компания 2016-01-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/594
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author A. Ya. Kravchenko
V. M. Provotorov
author_facet A. Ya. Kravchenko
V. M. Provotorov
author_sort A. Ya. Kravchenko
collection DOAJ
description Aim. To study efficacy of testosterone undecanoate (TU) therapy in men with stable angina and androgen deficiency.Material and methods. The serum testosterone level was detected in 247 men (aged 51,6±1,8 y.o.) with stable effort angina. 60 patients with androgen deficiency additionally to basic angina therapy received TU (120-160 mg daily). 54 patients with androgen deficiency (control group) received only basic angina therapy. Dynamics of clinical and ECG manifestations of myocardial ischemia and quality of life (QOL) parameters was studied.Results. Androgen deficiency is revealed in 114 (46,2%) of patients. Therapy with TU during 3 months resulted in reduction of angina attacks and extent of myocardial ischemia (according to Holter ECG monitoring and stress test) as well as QOL improvement.Conclusion. Androgen deficiency is observed in 46,2% of men with stable angina. TU increases of antianginal therapy efficacy, improves QOL and is well tolerated.
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spelling doaj.art-9f3e94e7b40b4470913e30d467ff38272024-12-04T11:48:04ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-0151374110.20996/1819-6446-2009-5-1-37-41593CLINICAL EFFECT OF TESTOSTERONE IN MEN WITH STABLE ANGINAA. Ya. Kravchenko0V. M. Provotorov1Voronezh State Medical Academy named after N.N. BurdenkoVoronezh State Medical Academy named after N.N. BurdenkoAim. To study efficacy of testosterone undecanoate (TU) therapy in men with stable angina and androgen deficiency.Material and methods. The serum testosterone level was detected in 247 men (aged 51,6±1,8 y.o.) with stable effort angina. 60 patients with androgen deficiency additionally to basic angina therapy received TU (120-160 mg daily). 54 patients with androgen deficiency (control group) received only basic angina therapy. Dynamics of clinical and ECG manifestations of myocardial ischemia and quality of life (QOL) parameters was studied.Results. Androgen deficiency is revealed in 114 (46,2%) of patients. Therapy with TU during 3 months resulted in reduction of angina attacks and extent of myocardial ischemia (according to Holter ECG monitoring and stress test) as well as QOL improvement.Conclusion. Androgen deficiency is observed in 46,2% of men with stable angina. TU increases of antianginal therapy efficacy, improves QOL and is well tolerated.https://www.rpcardio.online/jour/article/view/594stable anginamale sexandrogen deficiencytestosterone undecanoate
spellingShingle A. Ya. Kravchenko
V. M. Provotorov
CLINICAL EFFECT OF TESTOSTERONE IN MEN WITH STABLE ANGINA
Рациональная фармакотерапия в кардиологии
stable angina
male sex
androgen deficiency
testosterone undecanoate
title CLINICAL EFFECT OF TESTOSTERONE IN MEN WITH STABLE ANGINA
title_full CLINICAL EFFECT OF TESTOSTERONE IN MEN WITH STABLE ANGINA
title_fullStr CLINICAL EFFECT OF TESTOSTERONE IN MEN WITH STABLE ANGINA
title_full_unstemmed CLINICAL EFFECT OF TESTOSTERONE IN MEN WITH STABLE ANGINA
title_short CLINICAL EFFECT OF TESTOSTERONE IN MEN WITH STABLE ANGINA
title_sort clinical effect of testosterone in men with stable angina
topic stable angina
male sex
androgen deficiency
testosterone undecanoate
url https://www.rpcardio.online/jour/article/view/594
work_keys_str_mv AT ayakravchenko clinicaleffectoftestosteroneinmenwithstableangina
AT vmprovotorov clinicaleffectoftestosteroneinmenwithstableangina