BTK inhibitors in the treatment of hematological malignancies and inflammatory diseases: mechanisms and clinical studies
Abstract Bruton’s tyrosine kinase (BTK) is an essential component of multiple signaling pathways that regulate B cell and myeloid cell proliferation, survival, and functions, making it a promising therapeutic target for various B cell malignancies and inflammatory diseases. Five small molecule inhib...
المؤلفون الرئيسيون: | , , , , |
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التنسيق: | مقال |
اللغة: | English |
منشور في: |
BMC
2022-10-01
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سلاسل: | Journal of Hematology & Oncology |
الموضوعات: | |
الوصول للمادة أونلاين: | https://doi.org/10.1186/s13045-022-01353-w |