BTK inhibitors in the treatment of hematological malignancies and inflammatory diseases: mechanisms and clinical studies

Abstract Bruton’s tyrosine kinase (BTK) is an essential component of multiple signaling pathways that regulate B cell and myeloid cell proliferation, survival, and functions, making it a promising therapeutic target for various B cell malignancies and inflammatory diseases. Five small molecule inhib...

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书目详细资料
Main Authors: Aqu Alu, Hong Lei, Xuejiao Han, Yuquan Wei, Xiawei Wei
格式: 文件
语言:English
出版: BMC 2022-10-01
丛编:Journal of Hematology & Oncology
主题:
在线阅读:https://doi.org/10.1186/s13045-022-01353-w