The effectiveness of fracture liaison services in patients with hip fractures: A systematic review and meta-analysis of randomized controlled trials
Background: In recent years, fracture liaison services (FLS) have been applied for hip fractures; however, their effectiveness remains uncertain. Objective: To evaluate the effectiveness of FLS in patients with hip fractures. Design: A systematic review and meta-analysis of randomized controlled tri...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-10-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023080465 |
| _version_ | 1797646465041956864 |
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| author | Chengli Yan Yuyu Chen Jia Cao Kai Fang Lifang Shao Yaping Luo Lili Yang |
| author_facet | Chengli Yan Yuyu Chen Jia Cao Kai Fang Lifang Shao Yaping Luo Lili Yang |
| author_sort | Chengli Yan |
| collection | DOAJ |
| description | Background: In recent years, fracture liaison services (FLS) have been applied for hip fractures; however, their effectiveness remains uncertain. Objective: To evaluate the effectiveness of FLS in patients with hip fractures. Design: A systematic review and meta-analysis of randomized controlled trials. Data sources: Embase, PubMed, Cochrane Library, Ebsco, Ovid, Web of Science, Medline, CNKI, Wangfang, and Vip were searched from their date of inception to March 2023. Two researchers screened the literature based on the inclusion and exclusion criteria, evaluated the quality, extracted data, and conducted a meta-analysis using ReviewManager 5.4. Results: After screening, 12 randomised controlled trials (RCT) including 2136 patients were used in the meta-analysis. The primary outcomes were hip function rate of recurrent fracture, medication adherence, and degree of weakness. FLS improved hip function in patients with hip fractures [MD = 9.37, 95 % CI (7.69, 11.06), P < 0.0001], P < 0.0001], medication adherence [OR = 10.59, 95 % CI (1.64, 68.41), P＜0.0001], degree of weakness [MD = −1.45, 95%CI (−1.68，-1.23), P＜0.0001], and reduced the rate of recurrent fractures [OR = 0.60, 95 % CI (0.44, 0.82). Conclusion: Implementation of the FLS management model was beneficial for patients with hip fractures. It can positively impact the prognosis of patients with hip fractures by improving hip function, reducing the rate of recurrent fractures, and improving medication adherence and degree of weakness. |
| first_indexed | 2024-03-11T15:03:00Z |
| format | Article |
| id | doaj.art-9f4047491d764ac4ab6bf46c82cdd3f9 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-11T15:03:00Z |
| publishDate | 2023-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-9f4047491d764ac4ab6bf46c82cdd3f92023-10-30T06:07:37ZengElsevierHeliyon2405-84402023-10-01910e20838The effectiveness of fracture liaison services in patients with hip fractures: A systematic review and meta-analysis of randomized controlled trialsChengli Yan0Yuyu Chen1Jia Cao2Kai Fang3Lifang Shao4Yaping Luo5Lili Yang6Department of Nursing, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, ChinaDepartment of Nursing, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, ChinaNursing Department, Dazhou Central Hospital, Sichuan, China; Corresponding author. Nursing Department, Dazhou Central Hospital, 56th Nanyuemiao street, Tonchuan District, Dazhou City, Sichuan Province 635000, ChinaDepartment of Information, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, ChinaDepartment of Nursing, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, ChinaDepartment of Nursing, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, ChinaDepartment of Nursing, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, China; Corresponding author. Nursing Department, The Fourth Affiliated Hospital Zhejiang University School of Medicine, 1st Shangcheng Avenue, Yiwu, Zhejiang Province 322000, China.Background: In recent years, fracture liaison services (FLS) have been applied for hip fractures; however, their effectiveness remains uncertain. Objective: To evaluate the effectiveness of FLS in patients with hip fractures. Design: A systematic review and meta-analysis of randomized controlled trials. Data sources: Embase, PubMed, Cochrane Library, Ebsco, Ovid, Web of Science, Medline, CNKI, Wangfang, and Vip were searched from their date of inception to March 2023. Two researchers screened the literature based on the inclusion and exclusion criteria, evaluated the quality, extracted data, and conducted a meta-analysis using ReviewManager 5.4. Results: After screening, 12 randomised controlled trials (RCT) including 2136 patients were used in the meta-analysis. The primary outcomes were hip function rate of recurrent fracture, medication adherence, and degree of weakness. FLS improved hip function in patients with hip fractures [MD = 9.37, 95 % CI (7.69, 11.06), P < 0.0001], P < 0.0001], medication adherence [OR = 10.59, 95 % CI (1.64, 68.41), P＜0.0001], degree of weakness [MD = −1.45, 95%CI (−1.68，-1.23), P＜0.0001], and reduced the rate of recurrent fractures [OR = 0.60, 95 % CI (0.44, 0.82). Conclusion: Implementation of the FLS management model was beneficial for patients with hip fractures. It can positively impact the prognosis of patients with hip fractures by improving hip function, reducing the rate of recurrent fractures, and improving medication adherence and degree of weakness.http://www.sciencedirect.com/science/article/pii/S2405844023080465Fracture liaison serviceHip fractureMeta-analysis |
| spellingShingle | Chengli Yan Yuyu Chen Jia Cao Kai Fang Lifang Shao Yaping Luo Lili Yang The effectiveness of fracture liaison services in patients with hip fractures: A systematic review and meta-analysis of randomized controlled trials Heliyon Fracture liaison service Hip fracture Meta-analysis |
| title | The effectiveness of fracture liaison services in patients with hip fractures: A systematic review and meta-analysis of randomized controlled trials |
| title_full | The effectiveness of fracture liaison services in patients with hip fractures: A systematic review and meta-analysis of randomized controlled trials |
| title_fullStr | The effectiveness of fracture liaison services in patients with hip fractures: A systematic review and meta-analysis of randomized controlled trials |
| title_full_unstemmed | The effectiveness of fracture liaison services in patients with hip fractures: A systematic review and meta-analysis of randomized controlled trials |
| title_short | The effectiveness of fracture liaison services in patients with hip fractures: A systematic review and meta-analysis of randomized controlled trials |
| title_sort | effectiveness of fracture liaison services in patients with hip fractures a systematic review and meta analysis of randomized controlled trials |
| topic | Fracture liaison service Hip fracture Meta-analysis |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023080465 |
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