DDIT4 S‐Nitrosylation Aids p38‐MAPK Signaling Complex Assembly to Promote Hepatic Reactive Oxygen Species Production

DDIT4 S‐Nitrosylation Aids p38‐MAPK Signaling Complex Assembly to Promote Hepatic Reactive Oxygen Species Production

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Abstract Mitogen‐activated protein kinase (MAPK) signaling plays a significant role in reactive oxygen species (ROS) production. The authors have previously shown that Brahma‐related gene 1 (BRG1), a chromatin remodeling protein, contributes to hepatic ROS accumulation in multiple animal and cellula...

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Bibliographic Details
Main Authors: Zilong Li, Qianwen Zhao, Yunjie Lu, Yangxi Zhang, Luyang Li, Min Li, Xuemin Chen, Donglin Sun, Yunfei Duan, Yong Xu
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Advanced Science
Subjects:
liver injury
p38 signaling
post‐translational modification
reactive oxygen species (ROS)
transcriptional regulation
Online Access:https://doi.org/10.1002/advs.202101957

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