Metformin Ameliorates Postoperative Cognitive Dysfunction through Regulation of the AMPK/SIRT1 Pathway

Metformin Ameliorates Postoperative Cognitive Dysfunction through Regulation of the AMPK/SIRT1 Pathway

Background: Postoperative cognitive dysfunction (POCD) is a common postoperative complication in elderly patients. The purpose of this study was to investigate the mechanism through which metformin improves postoperative cognitive function. Methods: In the in vivo experiment, 18-month-old Sprague–Da...

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Bibliographic Details
Main Authors:	Peiyu Jia, Ji Che, Junfeng Zhang, Haibing Li, Quanhong Zhou, Yong Guo
Format:	Article
Language:	English
Published:	IMR Press 2023-08-01
Series:	Journal of Integrative Neuroscience
Subjects:	metformin postoperative cognitive dysfunction autophagy oxidative stress ampk/sirt1 pathway
Online Access:	https://www.imrpress.com/journal/JIN/22/5/10.31083/j.jin2205110

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