Discrete molecular dynamics can predict helical prestructured motifs in disordered proteins.

Discrete molecular dynamics can predict helical prestructured motifs in disordered proteins.

Intrinsically disordered proteins (IDPs) lack a stable tertiary structure, but their short binding regions termed Pre-Structured Motifs (PreSMo) can form transient secondary structure elements in solution. Although disordered proteins are crucial in many biological processes and designing strategies...

Полное описание

Библиографические подробности
Главные авторы:	Dániel Szöllősi, Tamás Horváth, Kyou-Hoon Han, Nikolay V Dokholyan, Péter Tompa, Lajos Kalmár, Tamás Hegedűs
Формат:	Статья
Язык:	English
Опубликовано:	Public Library of Science (PLoS) 2014-01-01
Серии:	PLoS ONE
Online-ссылка:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0095795&type=printable

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