DNA Damage Repair Classifier Defines Distinct Groups in Hepatocellular Carcinoma

DNA Damage Repair Classifier Defines Distinct Groups in Hepatocellular Carcinoma

DNA repair pathways have been associated with variability in hepatocellular carcinoma (HCC) clinical outcomes, but the mechanism through which DNA repair varies as a function of liver regeneration and other HCC characteristics is poorly understood. We curated a panel of 199 genes representing 15 DNA...

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Bibliographic Details
Main Authors: Markia A. Smith, Sarah C. Van Alsten, Andrea Walens, Jeffrey S. Damrauer, Ugwuji N. Maduekwe, Russell R. Broaddus, Michael I. Love, Melissa A. Troester, Katherine A. Hoadley
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
hepatocellular carcinoma
HCC
DNA repair
liver regeneration
p53
Online Access:https://www.mdpi.com/2072-6694/14/17/4282

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