Dose, duration, and cost: opportunities to improve use of long-term oral antibiotics for people with rosacea
Background: Systemic antibiotics are often used to treat rosacea and tetracyclines are the most common antibiotic prescribed; however, there is ambiguity among clinical guideline suggestions. Importantly, there is an increasing call to all clinicians to curtail antibiotic use. Objective: To investig...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-01-01
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| Series: | Journal of Dermatological Treatment |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09546634.2018.1468069 |
| _version_ | 1797683753519153152 |
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| author | Joanne S. Rill Hadar Lev-Tov Guodong Liu Joslyn S. Kirby |
| author_facet | Joanne S. Rill Hadar Lev-Tov Guodong Liu Joslyn S. Kirby |
| author_sort | Joanne S. Rill |
| collection | DOAJ |
| description | Background: Systemic antibiotics are often used to treat rosacea and tetracyclines are the most common antibiotic prescribed; however, there is ambiguity among clinical guideline suggestions. Importantly, there is an increasing call to all clinicians to curtail antibiotic use. Objective: To investigate the utilization and cost of long-term oral antibiotic use for the treatment of rosacea, including ocular rosacea. Methods: This was a retrospective cohort study of MarketScan® Commercial Claims and Encounters database, from January 1, 2005 through December 31, 2014. Claim data were used to determine the duration and costs of antibiotic treatment among adults with rosacea. Results: The sample included 72,411 patients. The mean (SD) duration of long-term antibiotic treatment was 87.68 (145.99) days and for patients with ocular rosacea was slightly longer, 108.34 (176.74) days [p < .0001]. The majority of antibiotic courses were shorter than 3 months (80.04%) for the entire sample and the subset with ocular rosacea (53.64% [p = .007]). Limitations: Patient adherence is uncertain and database lacks information on rosacea severity and clinical outcomes. Conclusions: The majority of oral antibiotic course durations follow guidelines. Costs of antibiotic therapy were lower for shorter courses and those utilizing generic medications; the cost-effectiveness of these modifications has not been investigated. |
| first_indexed | 2024-03-12T00:19:24Z |
| format | Article |
| id | doaj.art-9f52844e18b046ceb90e495688925dcf |
| institution | Directory Open Access Journal |
| issn | 0954-6634 1471-1753 |
| language | English |
| last_indexed | 2024-03-12T00:19:24Z |
| publishDate | 2019-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj.art-9f52844e18b046ceb90e495688925dcf2023-09-15T14:08:32ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532019-01-01301636710.1080/09546634.2018.14680691468069Dose, duration, and cost: opportunities to improve use of long-term oral antibiotics for people with rosaceaJoanne S. Rill0Hadar Lev-Tov1Guodong Liu2Joslyn S. Kirby3Dermatology Associates of LancasterUniversity of MiamiPenn State Milton S. Hershey Medical CenterPenn State Milton S. Hershey Medical CenterBackground: Systemic antibiotics are often used to treat rosacea and tetracyclines are the most common antibiotic prescribed; however, there is ambiguity among clinical guideline suggestions. Importantly, there is an increasing call to all clinicians to curtail antibiotic use. Objective: To investigate the utilization and cost of long-term oral antibiotic use for the treatment of rosacea, including ocular rosacea. Methods: This was a retrospective cohort study of MarketScan® Commercial Claims and Encounters database, from January 1, 2005 through December 31, 2014. Claim data were used to determine the duration and costs of antibiotic treatment among adults with rosacea. Results: The sample included 72,411 patients. The mean (SD) duration of long-term antibiotic treatment was 87.68 (145.99) days and for patients with ocular rosacea was slightly longer, 108.34 (176.74) days [p < .0001]. The majority of antibiotic courses were shorter than 3 months (80.04%) for the entire sample and the subset with ocular rosacea (53.64% [p = .007]). Limitations: Patient adherence is uncertain and database lacks information on rosacea severity and clinical outcomes. Conclusions: The majority of oral antibiotic course durations follow guidelines. Costs of antibiotic therapy were lower for shorter courses and those utilizing generic medications; the cost-effectiveness of these modifications has not been investigated.http://dx.doi.org/10.1080/09546634.2018.1468069rosaceaocular rosaceaoral antibioticsdurationtreatment guidelinescost |
| spellingShingle | Joanne S. Rill Hadar Lev-Tov Guodong Liu Joslyn S. Kirby Dose, duration, and cost: opportunities to improve use of long-term oral antibiotics for people with rosacea Journal of Dermatological Treatment rosacea ocular rosacea oral antibiotics duration treatment guidelines cost |
| title | Dose, duration, and cost: opportunities to improve use of long-term oral antibiotics for people with rosacea |
| title_full | Dose, duration, and cost: opportunities to improve use of long-term oral antibiotics for people with rosacea |
| title_fullStr | Dose, duration, and cost: opportunities to improve use of long-term oral antibiotics for people with rosacea |
| title_full_unstemmed | Dose, duration, and cost: opportunities to improve use of long-term oral antibiotics for people with rosacea |
| title_short | Dose, duration, and cost: opportunities to improve use of long-term oral antibiotics for people with rosacea |
| title_sort | dose duration and cost opportunities to improve use of long term oral antibiotics for people with rosacea |
| topic | rosacea ocular rosacea oral antibiotics duration treatment guidelines cost |
| url | http://dx.doi.org/10.1080/09546634.2018.1468069 |
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