Development of anti-membrane type 1-matrix metalloproteinase nanobodies as immunoPET probes for triple negative breast cancer imaging

Development of anti-membrane type 1-matrix metalloproteinase nanobodies as immunoPET probes for triple negative breast cancer imaging

Triple-negative breast cancer (TNBC) is characterized by aggressiveness and high rates of metastasis. The identification of relevant biomarkers is crucial to improve outcomes for TNBC patients. Membrane type 1-matrix metalloproteinase (MT1-MMP) could be a good candidate because its expression has be...

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Bibliographic Details
Main Authors: Francisca Mulero, Marta Oteo, Guillermo Garaulet, Natalia Magro, Lluvia Rebollo, Guillermo Medrano, Clara Santiveri, Eduardo Romero, Ricela E. Sellek, Yago Margolles, Ramón Campos-Olivas, Alicia G. Arroyo, Luis Angel Fernández, Miguel Angel Morcillo, Jorge L. Martínez-Torrecuadrada
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Medicine
Subjects:
immunoPET
MT1-MMP
nanobodies
gallium-68
TNBC (triple negative breast cancer)
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1058455/full

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