Hand eczema: possible risks and choice of therapy
Hand eczema is a common disease – up to 5% in the general population. In addition, eczema is closely related to atopy and, like atopic dermatitis, to a mutation in the FLG gene. In addition to genetic factors, eczema is caused by external irritants and toxic substances. Eczema often occurs in famili...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Remedium Group LLC
2022-03-01
|
| Series: | Медицинский совет |
| Subjects: | |
| Online Access: | https://www.med-sovet.pro/jour/article/view/6732 |
| _version_ | 1797841513415180288 |
|---|---|
| author | L. R. Sakaniya O. Yu. Smolkina I. M. Korsunskaya |
| author_facet | L. R. Sakaniya O. Yu. Smolkina I. M. Korsunskaya |
| author_sort | L. R. Sakaniya |
| collection | DOAJ |
| description | Hand eczema is a common disease – up to 5% in the general population. In addition, eczema is closely related to atopy and, like atopic dermatitis, to a mutation in the FLG gene. In addition to genetic factors, eczema is caused by external irritants and toxic substances. Eczema often occurs in families with atopic diseases, including asthma, allergic rhinitis/hay fever (and food allergies), and atopic dermatitis. These diseases share a common pathogenesis and often occur together in the same person and/or family. Eczematous rashes are often accompanied by itching. This symptom can lead not only to sleep disturbances but also to secondary infections. According to some data, the rate of infections in eczema can be more than 70%. In such cases, the drugs of choice are combined glucocorticosteroids (GC), which in addition to GC contain an antimycotic and an antibiotic. Our practical experience shows the high effectiveness of the combination of beclomethasone dipropionate, gentamicin, and clotrimazole not only in cases of eczema complicated by secondary infection but also in patients with other infected chronic dermatoses. This article reviews these and other practical aspects and problems in the treatment of hand eczema, discusses the etiological factors that lead to the development of the disease, and presents current data from clinical recommendations and guidelines for the treatment of eczema. |
| first_indexed | 2024-04-09T16:32:02Z |
| format | Article |
| id | doaj.art-9f57842e2b534ce68f230b759b5834c6 |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:32:02Z |
| publishDate | 2022-03-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-9f57842e2b534ce68f230b759b5834c62023-04-23T06:57:04ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902022-03-0103323610.21518/2079-701X-2022-16-3-32-366053Hand eczema: possible risks and choice of therapyL. R. Sakaniya0O. Yu. Smolkina1I. M. Korsunskaya2Center for Theoretical Problems of Physicochemical Pharmacology of the Russian Academy of Sciences; Moscow Scientific and Practical Center for Dermatovenereology and CosmetologyCenter for Theoretical Problems of Physicochemical Pharmacology of the Russian Academy of Sciences; Scientific and Clinical Consulting Center of Allergology and ImmunologyCenter for Theoretical Problems of Physicochemical Pharmacology of the Russian Academy of Sciences; Moscow Scientific and Practical Center for Dermatovenereology and CosmetologyHand eczema is a common disease – up to 5% in the general population. In addition, eczema is closely related to atopy and, like atopic dermatitis, to a mutation in the FLG gene. In addition to genetic factors, eczema is caused by external irritants and toxic substances. Eczema often occurs in families with atopic diseases, including asthma, allergic rhinitis/hay fever (and food allergies), and atopic dermatitis. These diseases share a common pathogenesis and often occur together in the same person and/or family. Eczematous rashes are often accompanied by itching. This symptom can lead not only to sleep disturbances but also to secondary infections. According to some data, the rate of infections in eczema can be more than 70%. In such cases, the drugs of choice are combined glucocorticosteroids (GC), which in addition to GC contain an antimycotic and an antibiotic. Our practical experience shows the high effectiveness of the combination of beclomethasone dipropionate, gentamicin, and clotrimazole not only in cases of eczema complicated by secondary infection but also in patients with other infected chronic dermatoses. This article reviews these and other practical aspects and problems in the treatment of hand eczema, discusses the etiological factors that lead to the development of the disease, and presents current data from clinical recommendations and guidelines for the treatment of eczema.https://www.med-sovet.pro/jour/article/view/6732eczemasecondary infectionbeclomethasone dipropionateclotrimazolegentamicin |
| spellingShingle | L. R. Sakaniya O. Yu. Smolkina I. M. Korsunskaya Hand eczema: possible risks and choice of therapy Медицинский совет eczema secondary infection beclomethasone dipropionate clotrimazole gentamicin |
| title | Hand eczema: possible risks and choice of therapy |
| title_full | Hand eczema: possible risks and choice of therapy |
| title_fullStr | Hand eczema: possible risks and choice of therapy |
| title_full_unstemmed | Hand eczema: possible risks and choice of therapy |
| title_short | Hand eczema: possible risks and choice of therapy |
| title_sort | hand eczema possible risks and choice of therapy |
| topic | eczema secondary infection beclomethasone dipropionate clotrimazole gentamicin |
| url | https://www.med-sovet.pro/jour/article/view/6732 |
| work_keys_str_mv | AT lrsakaniya handeczemapossiblerisksandchoiceoftherapy AT oyusmolkina handeczemapossiblerisksandchoiceoftherapy AT imkorsunskaya handeczemapossiblerisksandchoiceoftherapy |