Improving the coverage and accuracy of syphilis testing: The development of a novel rapid, point-of-care test for confirmatory testing of active syphilis infection and its early evaluation in China and South Africa

Improving the coverage and accuracy of syphilis testing: The development of a novel rapid, point-of-care test for confirmatory testing of active syphilis infection and its early evaluation in China and South Africa

Background: Current point-of-care tests (POCT) for syphilis, based on the detection of Treponema pallidum (TP) total antibodies, have limited capacity in distinguishing between active and past/treated syphilis. We report the development and early evaluation of a new prototype POCT based on the detec...

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Bibliographic Details
Main Authors: Minh D. Pham, Amy Wise, Mary L. Garcia, Huy Van, Shuning Zheng, Yasmin Mohamed, Yan Han, Wan-Hui Wei, Yue-Ping Yin, Xiang-Sheng Chen, Wayne Dimech, Susie Braniff, Karl-Günter Technau, Stanley Luchters, David A. Anderson
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:EClinicalMedicine
Subjects:
Syphilis
IgA
Diagnostic accuracy
Point of care test
South Africa
China
Online Access:http://www.sciencedirect.com/science/article/pii/S258953702030184X

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