A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves
The therapeutic implications of bicuspid aortic valve associations have come under scrutiny in the transcatheter aortic valve implantation era. We evaluate the spectrum of mitral valve disease in patients with bicuspid aortic valves to determine the need for closer echocardiographic scrutiny/follow-...
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BMC
2017-07-01
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| Series: | Echo Research and Practice |
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| Online Access: | http://www.echorespract.com/content/4/2/21.full |
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| author | Annari van Rensburg Philip Herbst Anton Doubell |
| author_facet | Annari van Rensburg Philip Herbst Anton Doubell |
| author_sort | Annari van Rensburg |
| collection | DOAJ |
| description | The therapeutic implications of bicuspid aortic valve associations have come under scrutiny in the transcatheter aortic valve implantation era. We evaluate the spectrum of mitral valve disease in patients with bicuspid aortic valves to determine the need for closer echocardiographic scrutiny/follow-up of the mitral valve. A retrospective analysis of echocardiograms done at a referral hospital over five years was conducted in patients with bicuspid aortic valves with special attention to congenital abnormalities of the mitral valve. One hundred and forty patients with a bicuspid aortic valve were included. A congenital mitral valve abnormality was present in eight (5.7%, P = 0.01) with a parachute mitral valve in four (2.8%), an accessory mitral valve leaflet in one (0.7%), mitral valve prolapse in one, a cleft in one and the novel finding of a trileaflet mitral valve in one. Minor abnormalities included an elongated anterior mitral valve leaflet (P < 0.001), the increased incidence of physiological mitral regurgitation (P < 0.001), abnormal papillary muscles (P = 0.002) and an additional chord or tendon in the left ventricle cavity (P = 0.007). Mitral valve abnormalities occur more commonly in patients with bicuspid aortic valves than matched healthy individuals. The study confirms that abnormalities in these patients extend beyond the aorta. These abnormalities did not have a significant functional effect. |
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| format | Article |
| id | doaj.art-9f59fe574af648f0b616c10345e8f71c |
| institution | Directory Open Access Journal |
| issn | 2055-0464 2055-0464 |
| language | English |
| last_indexed | 2024-04-13T18:03:48Z |
| publishDate | 2017-07-01 |
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| series | Echo Research and Practice |
| spelling | doaj.art-9f59fe574af648f0b616c10345e8f71c2022-12-22T02:36:09ZengBMCEcho Research and Practice2055-04642055-04642017-07-0142212810.1530/ERP-17-0016A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valvesAnnari van Rensburg0Philip Herbst1Anton Doubell2Division of Cardiology, Department of Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South AfricaDivision of Cardiology, Department of Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South AfricaDivision of Cardiology, Department of Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South AfricaThe therapeutic implications of bicuspid aortic valve associations have come under scrutiny in the transcatheter aortic valve implantation era. We evaluate the spectrum of mitral valve disease in patients with bicuspid aortic valves to determine the need for closer echocardiographic scrutiny/follow-up of the mitral valve. A retrospective analysis of echocardiograms done at a referral hospital over five years was conducted in patients with bicuspid aortic valves with special attention to congenital abnormalities of the mitral valve. One hundred and forty patients with a bicuspid aortic valve were included. A congenital mitral valve abnormality was present in eight (5.7%, P = 0.01) with a parachute mitral valve in four (2.8%), an accessory mitral valve leaflet in one (0.7%), mitral valve prolapse in one, a cleft in one and the novel finding of a trileaflet mitral valve in one. Minor abnormalities included an elongated anterior mitral valve leaflet (P < 0.001), the increased incidence of physiological mitral regurgitation (P < 0.001), abnormal papillary muscles (P = 0.002) and an additional chord or tendon in the left ventricle cavity (P = 0.007). Mitral valve abnormalities occur more commonly in patients with bicuspid aortic valves than matched healthy individuals. The study confirms that abnormalities in these patients extend beyond the aorta. These abnormalities did not have a significant functional effect.http://www.echorespract.com/content/4/2/21.fullbicuspid aortic valvemitral valvecongenital heart diseaseechocardiography |
| spellingShingle | Annari van Rensburg Philip Herbst Anton Doubell A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves Echo Research and Practice bicuspid aortic valve mitral valve congenital heart disease echocardiography |
| title | A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves |
| title_full | A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves |
| title_fullStr | A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves |
| title_full_unstemmed | A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves |
| title_short | A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves |
| title_sort | retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves |
| topic | bicuspid aortic valve mitral valve congenital heart disease echocardiography |
| url | http://www.echorespract.com/content/4/2/21.full |
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