Hemopexin and Cancer

Hemopexin is the plasma protein with the highest affinity for heme. Seminal studies have highlighted its role in different kinds of heme-associated disorders, but its implication in cancer has been neglected for a long time. Considering the emerging importance of heme in tumors, the present review p...

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Main Authors: Veronica Fiorito, Emanuela Tolosano
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/2/997
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author Veronica Fiorito
Emanuela Tolosano
author_facet Veronica Fiorito
Emanuela Tolosano
author_sort Veronica Fiorito
collection DOAJ
description Hemopexin is the plasma protein with the highest affinity for heme. Seminal studies have highlighted its role in different kinds of heme-associated disorders, but its implication in cancer has been neglected for a long time. Considering the emerging importance of heme in tumors, the present review proposes an update of the works investigating hemopexin involvement in cancer, with the attempt to stimulate further future studies on this topic.
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spelling doaj.art-9f5a39b3623a4523a7713efad90e0b992023-11-23T14:07:56ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-01-0123299710.3390/ijms23020997Hemopexin and CancerVeronica Fiorito0Emanuela Tolosano1Molecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, ItalyMolecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, ItalyHemopexin is the plasma protein with the highest affinity for heme. Seminal studies have highlighted its role in different kinds of heme-associated disorders, but its implication in cancer has been neglected for a long time. Considering the emerging importance of heme in tumors, the present review proposes an update of the works investigating hemopexin involvement in cancer, with the attempt to stimulate further future studies on this topic.https://www.mdpi.com/1422-0067/23/2/997hemopexincancerheme
spellingShingle Veronica Fiorito
Emanuela Tolosano
Hemopexin and Cancer
International Journal of Molecular Sciences
hemopexin
cancer
heme
title Hemopexin and Cancer
title_full Hemopexin and Cancer
title_fullStr Hemopexin and Cancer
title_full_unstemmed Hemopexin and Cancer
title_short Hemopexin and Cancer
title_sort hemopexin and cancer
topic hemopexin
cancer
heme
url https://www.mdpi.com/1422-0067/23/2/997
work_keys_str_mv AT veronicafiorito hemopexinandcancer
AT emanuelatolosano hemopexinandcancer