Hemopexin and Cancer
Hemopexin is the plasma protein with the highest affinity for heme. Seminal studies have highlighted its role in different kinds of heme-associated disorders, but its implication in cancer has been neglected for a long time. Considering the emerging importance of heme in tumors, the present review p...
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Format: | Article |
Language: | English |
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MDPI AG
2022-01-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | https://www.mdpi.com/1422-0067/23/2/997 |
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author | Veronica Fiorito Emanuela Tolosano |
author_facet | Veronica Fiorito Emanuela Tolosano |
author_sort | Veronica Fiorito |
collection | DOAJ |
description | Hemopexin is the plasma protein with the highest affinity for heme. Seminal studies have highlighted its role in different kinds of heme-associated disorders, but its implication in cancer has been neglected for a long time. Considering the emerging importance of heme in tumors, the present review proposes an update of the works investigating hemopexin involvement in cancer, with the attempt to stimulate further future studies on this topic. |
first_indexed | 2024-03-10T01:17:19Z |
format | Article |
id | doaj.art-9f5a39b3623a4523a7713efad90e0b99 |
institution | Directory Open Access Journal |
issn | 1661-6596 1422-0067 |
language | English |
last_indexed | 2024-03-10T01:17:19Z |
publishDate | 2022-01-01 |
publisher | MDPI AG |
record_format | Article |
series | International Journal of Molecular Sciences |
spelling | doaj.art-9f5a39b3623a4523a7713efad90e0b992023-11-23T14:07:56ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-01-0123299710.3390/ijms23020997Hemopexin and CancerVeronica Fiorito0Emanuela Tolosano1Molecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, ItalyMolecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, ItalyHemopexin is the plasma protein with the highest affinity for heme. Seminal studies have highlighted its role in different kinds of heme-associated disorders, but its implication in cancer has been neglected for a long time. Considering the emerging importance of heme in tumors, the present review proposes an update of the works investigating hemopexin involvement in cancer, with the attempt to stimulate further future studies on this topic.https://www.mdpi.com/1422-0067/23/2/997hemopexincancerheme |
spellingShingle | Veronica Fiorito Emanuela Tolosano Hemopexin and Cancer International Journal of Molecular Sciences hemopexin cancer heme |
title | Hemopexin and Cancer |
title_full | Hemopexin and Cancer |
title_fullStr | Hemopexin and Cancer |
title_full_unstemmed | Hemopexin and Cancer |
title_short | Hemopexin and Cancer |
title_sort | hemopexin and cancer |
topic | hemopexin cancer heme |
url | https://www.mdpi.com/1422-0067/23/2/997 |
work_keys_str_mv | AT veronicafiorito hemopexinandcancer AT emanuelatolosano hemopexinandcancer |