The Beneficial Effect of Physical Exercise on Cognitive Function in a Non-dementia Aging Chinese Population
Numerous observational studies have shown that physical exercise promotes cognition in the elderly, however, the results from randomized clinical trials (RCTs) are ambiguous. In addition, potential benefits of exercise in an elderly Chinese population have not been comprehensively addressed. In this...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-08-01
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| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fnagi.2019.00238/full |
| _version_ | 1818179553947811840 |
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| author | Sun Lin Yang Yang Qiu Qi Li Wei Nie Jing Zhang Jie Li Xia Xiao Shifu |
| author_facet | Sun Lin Yang Yang Qiu Qi Li Wei Nie Jing Zhang Jie Li Xia Xiao Shifu |
| author_sort | Sun Lin |
| collection | DOAJ |
| description | Numerous observational studies have shown that physical exercise promotes cognition in the elderly, however, the results from randomized clinical trials (RCTs) are ambiguous. In addition, potential benefits of exercise in an elderly Chinese population have not been comprehensively addressed. In this study, an investigation was launched which focused on the relationship between physical exercise and cognitive function, blood lipid profiles and brain anatomy in a non-dementia aging Chinese population. A total of 2074 non-dementia elderly subjects were included (self-selected exercise n = 1372; self-selected non-exercise n = 702). Amongst the subjects, 689 volunteered to receive blood lipid tests, 141 undergo brain magnetic resonance imaging (MRI), and 1399 receive a 1 year cognitive evaluation follow-up. The Beijing version of the Montreal Cognitive Assessment (MoCA) and the Mini-Mental States Examination (MMSE) were used to assess cognitive function. A significant difference in cognitive function was observed at the baseline and during the 1-year follow-up between the self-selected exercise and self-selected non-exercise groups, however, no significant differences in blood lipids and brain anatomy was evident. Physical exercise has a beneficial effect on cognition, particularly visuospatial function, and decreases the risk of dementia in a Chinese aging cohort. |
| first_indexed | 2024-12-11T21:05:43Z |
| format | Article |
| id | doaj.art-9f5dd6a49e5e497286ed816f07eb7fe0 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-12-11T21:05:43Z |
| publishDate | 2019-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-9f5dd6a49e5e497286ed816f07eb7fe02022-12-22T00:50:52ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652019-08-011110.3389/fnagi.2019.00238477181The Beneficial Effect of Physical Exercise on Cognitive Function in a Non-dementia Aging Chinese PopulationSun Lin0Yang Yang1Qiu Qi2Li Wei3Nie Jing4Zhang Jie5Li Xia6Xiao Shifu7Alzheimer’s Disease and Related Disorders Center, Department of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShanghai I-Zhaohu Senior Care Services Co., Ltd., Shanghai, ChinaAlzheimer’s Disease and Related Disorders Center, Department of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaAlzheimer’s Disease and Related Disorders Center, Department of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaAlzheimer’s Disease and Related Disorders Center, Department of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaKey Laboratory of Arrhythmias, Ministry of Education, Shanghai East Hospital, Tong Ji University School of Medicine, Shanghai, ChinaAlzheimer’s Disease and Related Disorders Center, Department of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaAlzheimer’s Disease and Related Disorders Center, Department of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaNumerous observational studies have shown that physical exercise promotes cognition in the elderly, however, the results from randomized clinical trials (RCTs) are ambiguous. In addition, potential benefits of exercise in an elderly Chinese population have not been comprehensively addressed. In this study, an investigation was launched which focused on the relationship between physical exercise and cognitive function, blood lipid profiles and brain anatomy in a non-dementia aging Chinese population. A total of 2074 non-dementia elderly subjects were included (self-selected exercise n = 1372; self-selected non-exercise n = 702). Amongst the subjects, 689 volunteered to receive blood lipid tests, 141 undergo brain magnetic resonance imaging (MRI), and 1399 receive a 1 year cognitive evaluation follow-up. The Beijing version of the Montreal Cognitive Assessment (MoCA) and the Mini-Mental States Examination (MMSE) were used to assess cognitive function. A significant difference in cognitive function was observed at the baseline and during the 1-year follow-up between the self-selected exercise and self-selected non-exercise groups, however, no significant differences in blood lipids and brain anatomy was evident. Physical exercise has a beneficial effect on cognition, particularly visuospatial function, and decreases the risk of dementia in a Chinese aging cohort.https://www.frontiersin.org/article/10.3389/fnagi.2019.00238/fullexercisecognitive functiondementiabrain anatomylipid |
| spellingShingle | Sun Lin Yang Yang Qiu Qi Li Wei Nie Jing Zhang Jie Li Xia Xiao Shifu The Beneficial Effect of Physical Exercise on Cognitive Function in a Non-dementia Aging Chinese Population Frontiers in Aging Neuroscience exercise cognitive function dementia brain anatomy lipid |
| title | The Beneficial Effect of Physical Exercise on Cognitive Function in a Non-dementia Aging Chinese Population |
| title_full | The Beneficial Effect of Physical Exercise on Cognitive Function in a Non-dementia Aging Chinese Population |
| title_fullStr | The Beneficial Effect of Physical Exercise on Cognitive Function in a Non-dementia Aging Chinese Population |
| title_full_unstemmed | The Beneficial Effect of Physical Exercise on Cognitive Function in a Non-dementia Aging Chinese Population |
| title_short | The Beneficial Effect of Physical Exercise on Cognitive Function in a Non-dementia Aging Chinese Population |
| title_sort | beneficial effect of physical exercise on cognitive function in a non dementia aging chinese population |
| topic | exercise cognitive function dementia brain anatomy lipid |
| url | https://www.frontiersin.org/article/10.3389/fnagi.2019.00238/full |
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