Secondary Hypertension due to a Renin-secreting Juxtaglomerular Cell Tumor
A juxtaglomerular cell tumor (JCT) is a rare, renin-secreting tumor of the kidney and can cause hypertension. JCT is pathologically benign, and resection of the tumor is curative for hypertension. We report the case of a 17-year-old girl who had hypertension and hypokalemia for 1 year. Laboratory st...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2010-03-01
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| Series: | Journal of the Formosan Medical Association |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664610600472 |
| _version_ | 1828802985825665024 |
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| author | Shih-Yi Lin Wayne-Young Liu Wen-Chi Chen Rong-Hsing Chen |
| author_facet | Shih-Yi Lin Wayne-Young Liu Wen-Chi Chen Rong-Hsing Chen |
| author_sort | Shih-Yi Lin |
| collection | DOAJ |
| description | A juxtaglomerular cell tumor (JCT) is a rare, renin-secreting tumor of the kidney and can cause hypertension. JCT is pathologically benign, and resection of the tumor is curative for hypertension. We report the case of a 17-year-old girl who had hypertension and hypokalemia for 1 year. Laboratory studies showed increased basal plasma renin activity, but normal serum aldosterone level. Abdominal computed tomography disclosed a 2 cm solid mass in the left kidney. However, renal vein sampling and captopril test results were equivocal. Partial nephrectomy was performed and histologic examination demonstrated typical features of JCT. Hypertension and hypokalemia completely resolved postoperatively. JCT should be considered when investigating hypertensive individuals with high plasma renin activity. |
| first_indexed | 2024-12-12T07:13:53Z |
| format | Article |
| id | doaj.art-9f5dff1c906a4cf2b7c94217116ce618 |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-12-12T07:13:53Z |
| publishDate | 2010-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-9f5dff1c906a4cf2b7c94217116ce6182022-12-22T00:33:33ZengElsevierJournal of the Formosan Medical Association0929-66462010-03-01109323724010.1016/S0929-6646(10)60047-2Secondary Hypertension due to a Renin-secreting Juxtaglomerular Cell TumorShih-Yi Lin0Wayne-Young Liu1Wen-Chi Chen2Rong-Hsing Chen3Department of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, TaiwanDepartment of Urology, Jen Ai Hospital, Taichung, TaiwanDepartment of Urology, China Medical University Hospital, China Medical University, Taichung, TaiwanDepartment of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, TaiwanA juxtaglomerular cell tumor (JCT) is a rare, renin-secreting tumor of the kidney and can cause hypertension. JCT is pathologically benign, and resection of the tumor is curative for hypertension. We report the case of a 17-year-old girl who had hypertension and hypokalemia for 1 year. Laboratory studies showed increased basal plasma renin activity, but normal serum aldosterone level. Abdominal computed tomography disclosed a 2 cm solid mass in the left kidney. However, renal vein sampling and captopril test results were equivocal. Partial nephrectomy was performed and histologic examination demonstrated typical features of JCT. Hypertension and hypokalemia completely resolved postoperatively. JCT should be considered when investigating hypertensive individuals with high plasma renin activity.http://www.sciencedirect.com/science/article/pii/S0929664610600472hypertensionjuxtaglomerular cellplasma renin activityrenin-secreting tumor |
| spellingShingle | Shih-Yi Lin Wayne-Young Liu Wen-Chi Chen Rong-Hsing Chen Secondary Hypertension due to a Renin-secreting Juxtaglomerular Cell Tumor Journal of the Formosan Medical Association hypertension juxtaglomerular cell plasma renin activity renin-secreting tumor |
| title | Secondary Hypertension due to a Renin-secreting Juxtaglomerular Cell Tumor |
| title_full | Secondary Hypertension due to a Renin-secreting Juxtaglomerular Cell Tumor |
| title_fullStr | Secondary Hypertension due to a Renin-secreting Juxtaglomerular Cell Tumor |
| title_full_unstemmed | Secondary Hypertension due to a Renin-secreting Juxtaglomerular Cell Tumor |
| title_short | Secondary Hypertension due to a Renin-secreting Juxtaglomerular Cell Tumor |
| title_sort | secondary hypertension due to a renin secreting juxtaglomerular cell tumor |
| topic | hypertension juxtaglomerular cell plasma renin activity renin-secreting tumor |
| url | http://www.sciencedirect.com/science/article/pii/S0929664610600472 |
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