Modification of 6,7-Dichloro-5,8-Quinolinedione at C2 Position: Synthesis, Quantum Chemical Properties, and Activity against DT-Diaphorase Enzyme
This research presents a synthesis and characterization of new 6,7-dichloro-5,8-quinolinedione derivatives with various groups at the C2 position. Chemical structures were examined by the spectroscopic methods. The quantum chemical parameters calculated using the DFT method showed that these derivat...
Main Authors: | Monika Kadela-Tomanek, Ewa Bębenek, Elwira Chrobak |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
|
Series: | Applied Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3417/13/3/1530 |
Similar Items
-
5,8-Quinolinedione Attached to Quinone Derivatives: XRD Diffraction, Fourier Transform Infrared Spectra and Computational Analysis
by: Arkadiusz Sokal, et al.
Published: (2023-11-01) -
Spectroscopic Investigations, Computational Analysis and Molecular Docking to SAR-Cov-2 Targets Studies of 5,8-Quinolinedione Attached to Betulin Derivatives
by: Monika Kadela-Tomanek, et al.
Published: (2021-01-01) -
New Acetylenic Amine Derivatives of 5,8-Quinolinediones: Synthesis, Crystal Structure and Antiproliferative Activity
by: Monika Kadela-Tomanek, et al.
Published: (2017-01-01) -
Hybrids of 1,4-Quinone with Quinoline Derivatives: Synthesis, Biological Activity, and Molecular Docking with DT-Diaphorase (NQO1)
by: Monika Kadela-Tomanek, et al.
Published: (2022-09-01) -
The diverse functionality of NQO1 and its roles in redox control
by: David Ross, et al.
Published: (2021-05-01)