Expression of anti-chikungunya single-domain antibodies in transgenic Aedes aegypti reduces vector competence for chikungunya virus and Mayaro virus

Expression of anti-chikungunya single-domain antibodies in transgenic Aedes aegypti reduces vector competence for chikungunya virus and Mayaro virus

Chikungunya virus (CHIKV) and Mayaro virus (MAYV) are closely related alphaviruses that cause acute febrile illness accompanied by an incapacitating polyarthralgia that can persist for years following initial infection. In conjunction with sporadic outbreaks throughout the sub-tropical regions of th...

Full description

Bibliographic Details
Main Authors: Emily M. Webb, Austin Compton, Pallavi Rai, Christina Chuong, Sally L. Paulson, Zhijian Tu, James Weger-Lucarelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Microbiology
Subjects:
alphavirus
chikungunya virus (CHIKV)
Mayaro virus (MAYV)
single-domain antibodies (sdAb)
Aedes (Ae.) aegypti
transgenic mosquitoes
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1189176/full

Similar Items

Similar Items