Difference of Two Antiseptic Gels for the Treatment of Peri-Implant Mucositis on Plaque Index and Bleeding Score: A Randomized Controlled Clinical Study

Aim: To analyze and compare the effectiveness of two antibacterial gels in the treatment of mucositis. Methods: After signing the informed consent, in accordance with the Helsinki Declaration of 1975, revised in 2000, 21 patients were included in the study and divided by randomization into two group...

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Main Authors: Stefano Storelli, Giulia Palandrani, Barbara Manfredi, Eugenio Romeo, Dario De Martis, Claudia Todaro, Ruggero Rodriguez y Baena, Saturnino Marco Lupi
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/13/3/1288
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author Stefano Storelli
Giulia Palandrani
Barbara Manfredi
Eugenio Romeo
Dario De Martis
Claudia Todaro
Ruggero Rodriguez y Baena
Saturnino Marco Lupi
author_facet Stefano Storelli
Giulia Palandrani
Barbara Manfredi
Eugenio Romeo
Dario De Martis
Claudia Todaro
Ruggero Rodriguez y Baena
Saturnino Marco Lupi
author_sort Stefano Storelli
collection DOAJ
description Aim: To analyze and compare the effectiveness of two antibacterial gels in the treatment of mucositis. Methods: After signing the informed consent, in accordance with the Helsinki Declaration of 1975, revised in 2000, 21 patients were included in the study and divided by randomization into two groups. At the baseline, the modified bleeding index (mBI) and plaque index (PI) values were measured, and an oral hygiene and implant disinfection session was carried out. The session was repeated at 7, 15, and 30 days and after 2 and 3 months from the baseline. Two products were used—a bioadhesive gel in the test group and a 1% chlorhexidine gel in the control group. Results: Due to three dropouts, the final sample was composed of 18 patients. An improvement in periodontal indices was observed, similar to mBI and PI values, in both groups. There were no complications except for the appearance of pigmentations in the control group. Conclusions: The antibacterial power and effectiveness of the two gels are comparable. Considering the small sample size of the study cohort, further studies are needed to validate the results obtained from this pilot study.
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spelling doaj.art-9f6a5e10b4124d198f9c5d08c4154af22023-11-16T16:03:15ZengMDPI AGApplied Sciences2076-34172023-01-01133128810.3390/app13031288Difference of Two Antiseptic Gels for the Treatment of Peri-Implant Mucositis on Plaque Index and Bleeding Score: A Randomized Controlled Clinical StudyStefano Storelli0Giulia Palandrani1Barbara Manfredi2Eugenio Romeo3Dario De Martis4Claudia Todaro5Ruggero Rodriguez y Baena6Saturnino Marco Lupi7Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20142 Milan, ItalyDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, 20142 Milan, ItalyDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, 20142 Milan, ItalyDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, 20142 Milan, ItalyDepartment of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, ItalyDepartment of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, ItalyDepartment of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, ItalyDepartment of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, ItalyAim: To analyze and compare the effectiveness of two antibacterial gels in the treatment of mucositis. Methods: After signing the informed consent, in accordance with the Helsinki Declaration of 1975, revised in 2000, 21 patients were included in the study and divided by randomization into two groups. At the baseline, the modified bleeding index (mBI) and plaque index (PI) values were measured, and an oral hygiene and implant disinfection session was carried out. The session was repeated at 7, 15, and 30 days and after 2 and 3 months from the baseline. Two products were used—a bioadhesive gel in the test group and a 1% chlorhexidine gel in the control group. Results: Due to three dropouts, the final sample was composed of 18 patients. An improvement in periodontal indices was observed, similar to mBI and PI values, in both groups. There were no complications except for the appearance of pigmentations in the control group. Conclusions: The antibacterial power and effectiveness of the two gels are comparable. Considering the small sample size of the study cohort, further studies are needed to validate the results obtained from this pilot study.https://www.mdpi.com/2076-3417/13/3/1288peri-implant healthplaque controlbleeding indexplaque indexperi-implant mucositischlorhexidine
spellingShingle Stefano Storelli
Giulia Palandrani
Barbara Manfredi
Eugenio Romeo
Dario De Martis
Claudia Todaro
Ruggero Rodriguez y Baena
Saturnino Marco Lupi
Difference of Two Antiseptic Gels for the Treatment of Peri-Implant Mucositis on Plaque Index and Bleeding Score: A Randomized Controlled Clinical Study
Applied Sciences
peri-implant health
plaque control
bleeding index
plaque index
peri-implant mucositis
chlorhexidine
title Difference of Two Antiseptic Gels for the Treatment of Peri-Implant Mucositis on Plaque Index and Bleeding Score: A Randomized Controlled Clinical Study
title_full Difference of Two Antiseptic Gels for the Treatment of Peri-Implant Mucositis on Plaque Index and Bleeding Score: A Randomized Controlled Clinical Study
title_fullStr Difference of Two Antiseptic Gels for the Treatment of Peri-Implant Mucositis on Plaque Index and Bleeding Score: A Randomized Controlled Clinical Study
title_full_unstemmed Difference of Two Antiseptic Gels for the Treatment of Peri-Implant Mucositis on Plaque Index and Bleeding Score: A Randomized Controlled Clinical Study
title_short Difference of Two Antiseptic Gels for the Treatment of Peri-Implant Mucositis on Plaque Index and Bleeding Score: A Randomized Controlled Clinical Study
title_sort difference of two antiseptic gels for the treatment of peri implant mucositis on plaque index and bleeding score a randomized controlled clinical study
topic peri-implant health
plaque control
bleeding index
plaque index
peri-implant mucositis
chlorhexidine
url https://www.mdpi.com/2076-3417/13/3/1288
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