Partially Treated Typhoid fever Leading to Inevitable Abortion: A Case Report

A BSTRACT Typhoid fever continues to be a major public health problem in developing countries especially due to the challenging infrastructure and sanitation facilities. Many cases of abortions due to untreated Salmonella infection have been reported. The present report is about a 25-year-old fema...

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Main Authors: Ashima Jain, Namita Jaggi, Deepa Maheshwari
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2020-06-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/13749/44224_F(SHU)_CE[Ra1]_KM_PF1(AJ_KM)_PN(SL).pdf
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author Ashima Jain
Namita Jaggi
Deepa Maheshwari
author_facet Ashima Jain
Namita Jaggi
Deepa Maheshwari
author_sort Ashima Jain
collection DOAJ
description A BSTRACT Typhoid fever continues to be a major public health problem in developing countries especially due to the challenging infrastructure and sanitation facilities. Many cases of abortions due to untreated Salmonella infection have been reported. The present report is about a 25-year-old female who was inadequately treated for typhoid fever with suboptimal doses of oral ampicillin leading to inevitable abortion despite the infection being cleared from blood. Salmonella typhi was isolated from products of conception. The patient was treated with Ceftriaxone injections and has been found to be fine on follow-up visits. Typhoid during pregnancy needs to be treated with higher doses and preferably intravenous antibiotics instead of oral due to the increased volume of distribution and reduced tissue penetration of antibiotics in such patients.
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spelling doaj.art-9f6ff091d5404c799b8c9d5d9f2b54552022-12-21T19:13:41ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2020-06-01146QD01QD0210.7860/JCDR/2020/44224.13749Partially Treated Typhoid fever Leading to Inevitable Abortion: A Case ReportAshima Jain0Namita Jaggi1Deepa Maheshwari2Attending Consultant, Department of Laboratory Medicine, Artemis Hospitals, Gurugram, Haryana, India.Chairperson, Department of Labs and Infection Control, Artemis Hospitals, Gurugram, Haryana, India.Senior Consultant, Department of Obstetrics and Gynaecology, Artemis Hospitals, Gurugram, Haryana, India.A BSTRACT Typhoid fever continues to be a major public health problem in developing countries especially due to the challenging infrastructure and sanitation facilities. Many cases of abortions due to untreated Salmonella infection have been reported. The present report is about a 25-year-old female who was inadequately treated for typhoid fever with suboptimal doses of oral ampicillin leading to inevitable abortion despite the infection being cleared from blood. Salmonella typhi was isolated from products of conception. The patient was treated with Ceftriaxone injections and has been found to be fine on follow-up visits. Typhoid during pregnancy needs to be treated with higher doses and preferably intravenous antibiotics instead of oral due to the increased volume of distribution and reduced tissue penetration of antibiotics in such patients.https://jcdr.net/articles/PDF/13749/44224_F(SHU)_CE[Ra1]_KM_PF1(AJ_KM)_PN(SL).pdfampicillin dosagepregnancysalmonella typhi
spellingShingle Ashima Jain
Namita Jaggi
Deepa Maheshwari
Partially Treated Typhoid fever Leading to Inevitable Abortion: A Case Report
Journal of Clinical and Diagnostic Research
ampicillin dosage
pregnancy
salmonella typhi
title Partially Treated Typhoid fever Leading to Inevitable Abortion: A Case Report
title_full Partially Treated Typhoid fever Leading to Inevitable Abortion: A Case Report
title_fullStr Partially Treated Typhoid fever Leading to Inevitable Abortion: A Case Report
title_full_unstemmed Partially Treated Typhoid fever Leading to Inevitable Abortion: A Case Report
title_short Partially Treated Typhoid fever Leading to Inevitable Abortion: A Case Report
title_sort partially treated typhoid fever leading to inevitable abortion a case report
topic ampicillin dosage
pregnancy
salmonella typhi
url https://jcdr.net/articles/PDF/13749/44224_F(SHU)_CE[Ra1]_KM_PF1(AJ_KM)_PN(SL).pdf
work_keys_str_mv AT ashimajain partiallytreatedtyphoidfeverleadingtoinevitableabortionacasereport
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AT deepamaheshwari partiallytreatedtyphoidfeverleadingtoinevitableabortionacasereport