EDTA Chelation Therapy in the Treatment of Neurodegenerative Diseases: An Update
We have previously described the role played by toxic-metal burdens in the etiology of neurodegenerative diseases (ND). We herein report an updated evaluation of toxic-metal burdens in human subjects affected or not affected by ND or other chronic diseases. Each subject underwent a chelation test wi...
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| Format: | Article |
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MDPI AG
2020-08-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/8/8/269 |
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| author | Alessandro Fulgenzi Daniele Vietti Maria Elena Ferrero |
| author_facet | Alessandro Fulgenzi Daniele Vietti Maria Elena Ferrero |
| author_sort | Alessandro Fulgenzi |
| collection | DOAJ |
| description | We have previously described the role played by toxic-metal burdens in the etiology of neurodegenerative diseases (ND). We herein report an updated evaluation of toxic-metal burdens in human subjects affected or not affected by ND or other chronic diseases. Each subject underwent a chelation test with the chelating agent calcium disodium ethylenediaminetetraacetic acid (CaNA<sub>2</sub>EDTA or EDTA) to identify the presence of 20 toxic metals in urine samples using inductively coupled plasma mass spectrometry. Our results show the constant presence of toxic metals, such as lead, cadmium, cesium, and aluminum, in all examined subjects but the absence of beryllium and tellurium. Gadolinium was detected in patients undergoing diagnostic magnetic resonance imaging. The presence of toxic metals was always significantly more elevated in ND patients than in healthy controls. Treatment with EDTA chelation therapy removes toxic-metal burdens and improves patient symptoms. |
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| format | Article |
| id | doaj.art-9f71f56c0adf43b6abfa2b1b5b340e3c |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-10T18:00:13Z |
| publishDate | 2020-08-01 |
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| series | Biomedicines |
| spelling | doaj.art-9f71f56c0adf43b6abfa2b1b5b340e3c2023-11-20T08:54:51ZengMDPI AGBiomedicines2227-90592020-08-018826910.3390/biomedicines8080269EDTA Chelation Therapy in the Treatment of Neurodegenerative Diseases: An UpdateAlessandro Fulgenzi0Daniele Vietti1Maria Elena Ferrero2Department of Biomedical Sciences for Health, Università degli Studi di Milano, Via Mangiagalli, 31, 20133 Milan, ItalyDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Via Mangiagalli, 31, 20133 Milan, ItalyDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Via Mangiagalli, 31, 20133 Milan, ItalyWe have previously described the role played by toxic-metal burdens in the etiology of neurodegenerative diseases (ND). We herein report an updated evaluation of toxic-metal burdens in human subjects affected or not affected by ND or other chronic diseases. Each subject underwent a chelation test with the chelating agent calcium disodium ethylenediaminetetraacetic acid (CaNA<sub>2</sub>EDTA or EDTA) to identify the presence of 20 toxic metals in urine samples using inductively coupled plasma mass spectrometry. Our results show the constant presence of toxic metals, such as lead, cadmium, cesium, and aluminum, in all examined subjects but the absence of beryllium and tellurium. Gadolinium was detected in patients undergoing diagnostic magnetic resonance imaging. The presence of toxic metals was always significantly more elevated in ND patients than in healthy controls. Treatment with EDTA chelation therapy removes toxic-metal burdens and improves patient symptoms.https://www.mdpi.com/2227-9059/8/8/269EDTA chelation therapyneurodegenerative diseasesmetal detoxification |
| spellingShingle | Alessandro Fulgenzi Daniele Vietti Maria Elena Ferrero EDTA Chelation Therapy in the Treatment of Neurodegenerative Diseases: An Update Biomedicines EDTA chelation therapy neurodegenerative diseases metal detoxification |
| title | EDTA Chelation Therapy in the Treatment of Neurodegenerative Diseases: An Update |
| title_full | EDTA Chelation Therapy in the Treatment of Neurodegenerative Diseases: An Update |
| title_fullStr | EDTA Chelation Therapy in the Treatment of Neurodegenerative Diseases: An Update |
| title_full_unstemmed | EDTA Chelation Therapy in the Treatment of Neurodegenerative Diseases: An Update |
| title_short | EDTA Chelation Therapy in the Treatment of Neurodegenerative Diseases: An Update |
| title_sort | edta chelation therapy in the treatment of neurodegenerative diseases an update |
| topic | EDTA chelation therapy neurodegenerative diseases metal detoxification |
| url | https://www.mdpi.com/2227-9059/8/8/269 |
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