MiRNA-Regulated Pathways for Hypertrophic Cardiomyopathy: Network-Based Approach to Insight into Pathogenesis

MiRNA-Regulated Pathways for Hypertrophic Cardiomyopathy: Network-Based Approach to Insight into Pathogenesis

Hypertrophic cardiomyopathy (HCM) is the most common hereditary heart disease. The wide spread of high-throughput sequencing casts doubt on its monogenic nature, suggesting the presence of mechanisms of HCM development independent from mutations in sarcomeric genes. From this point of view, HCM may...

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Bibliographic Details
Main Authors: German Osmak, Natalia Baulina, Ivan Kiselev, Olga Favorova
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Genes
Subjects:
hypertrophic cardiomyopathy
human
myocardium
miRNA (microRNA)
network analysis
pathway analysis
Online Access:https://www.mdpi.com/2073-4425/12/12/2016

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