Stitching up broken DNA ends by FANCA

Stitching up broken DNA ends by FANCA

RAD52 rejoins resected broken DNA ends by mediating single-strand annealing. Our recent work elucidates that FANCA, a Fanconi anemia protein, also directly repairs double-strand breaks (DSBs) by catalyzing annealing of single-stranded DNA. FANCA and RAD52 likely play complementary roles to each othe...

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Bibliographic Details
Main Authors:	Anna Palovcak, Wenjun Liu, Fenghua Yuan, Yanbin Zhang
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2018-11-01
Series:	Molecular & Cellular Oncology
Subjects:	fanca fanconi anemia double strand break repair interstrand crosslink repair
Online Access:	http://dx.doi.org/10.1080/23723556.2018.1518101

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