Research progress on the role of STAT in the pathogenesis of dermatosis
Signal transducer and activator of transcription (STAT) proteins with transcriptional activity, which are involved in the pathogenesis and formation of skin lesions of atopic dermatitis, psoriasis, skin tumors and other dermatosis, and are related to the severity of dermatosis. Different STAT has di...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2021-08-01
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| Series: | Jichu yixue yu linchuang |
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| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200913.pdf |
| _version_ | 1797365800791703552 |
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| author | ZHOU Qiong-yan, LIN Wei, XU Su-ling, ZHAO Ke-yu |
| author_facet | ZHOU Qiong-yan, LIN Wei, XU Su-ling, ZHAO Ke-yu |
| author_sort | ZHOU Qiong-yan, LIN Wei, XU Su-ling, ZHAO Ke-yu |
| collection | DOAJ |
| description | Signal transducer and activator of transcription (STAT) proteins with transcriptional activity, which are involved in the pathogenesis and formation of skin lesions of atopic dermatitis, psoriasis, skin tumors and other dermatosis, and are related to the severity of dermatosis. Different STAT has different pathways in dermatosis. STAT regulate cell signal transduction, affect the expression of downstream factors, and exert biological effects. Further study of STAT expression level and targeted genes to explore the relationship between STAT and dermatosis will help to find potential therapeutic targets for dermatosis. |
| first_indexed | 2024-03-08T16:54:06Z |
| format | Article |
| id | doaj.art-9f78e50792e341a4839f049d87d525aa |
| institution | Directory Open Access Journal |
| issn | 1001-6325 |
| language | zho |
| last_indexed | 2024-03-08T16:54:06Z |
| publishDate | 2021-08-01 |
| publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
| record_format | Article |
| series | Jichu yixue yu linchuang |
| spelling | doaj.art-9f78e50792e341a4839f049d87d525aa2024-01-05T03:06:25ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252021-08-0141812051209Research progress on the role of STAT in the pathogenesis of dermatosisZHOU Qiong-yan, LIN Wei, XU Su-ling, ZHAO Ke-yu01. Department of Dermatology; 2. Department of Pharmacy, the Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020;;3. School of Medicine, Ningbo University, Ningbo 315211, ChinaSignal transducer and activator of transcription (STAT) proteins with transcriptional activity, which are involved in the pathogenesis and formation of skin lesions of atopic dermatitis, psoriasis, skin tumors and other dermatosis, and are related to the severity of dermatosis. Different STAT has different pathways in dermatosis. STAT regulate cell signal transduction, affect the expression of downstream factors, and exert biological effects. Further study of STAT expression level and targeted genes to explore the relationship between STAT and dermatosis will help to find potential therapeutic targets for dermatosis.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200913.pdfsignal transducer and activator of transcription(stat)|dermatosis|pathway |
| spellingShingle | ZHOU Qiong-yan, LIN Wei, XU Su-ling, ZHAO Ke-yu Research progress on the role of STAT in the pathogenesis of dermatosis Jichu yixue yu linchuang signal transducer and activator of transcription(stat)|dermatosis|pathway |
| title | Research progress on the role of STAT in the pathogenesis of dermatosis |
| title_full | Research progress on the role of STAT in the pathogenesis of dermatosis |
| title_fullStr | Research progress on the role of STAT in the pathogenesis of dermatosis |
| title_full_unstemmed | Research progress on the role of STAT in the pathogenesis of dermatosis |
| title_short | Research progress on the role of STAT in the pathogenesis of dermatosis |
| title_sort | research progress on the role of stat in the pathogenesis of dermatosis |
| topic | signal transducer and activator of transcription(stat)|dermatosis|pathway |
| url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200913.pdf |
| work_keys_str_mv | AT zhouqiongyanlinweixusulingzhaokeyu researchprogressontheroleofstatinthepathogenesisofdermatosis |