Genetic and epigenetic variation in the lineage specification of regulatory T cells
Regulatory T (Treg) cells, which suppress autoimmunity and other inflammatory states, are characterized by a distinct set of genetic elements controlling their gene expression. However, the extent of genetic and associated epigenetic variation in the Treg cell lineage and its possible relation to di...
Main Authors: | Aaron Arvey, Joris van der Veeken, George Plitas, Stephen S Rich, Patrick Concannon, Alexander Y Rudensky |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-10-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/07571 |
Similar Items
-
Extensive Homeostatic T Cell Phenotypic Variation within the Collaborative Cross
by: Jessica B. Graham, et al.
Published: (2017-11-01) -
Recent revelations and future directions using single-cell technologies in chronic lymphocytic leukemia
by: Blaž Oder, et al.
Published: (2023-04-01) -
Automatic detection of genomic regions with informative epigenetic patterns
by: Florencio Pazos, et al.
Published: (2018-11-01) -
Immunogenomics and human disease /
by: Falus, Andras
Published: (2006) -
Differential usage of DNA modifications in neurons, astrocytes, and microglia
by: Kyla B. Tooley, et al.
Published: (2023-11-01)