Assessment of acute kidney injury in dogs suffering from babesiosis and leptospirosis
Acute kidney injury (AKI) is a serious complication of infectious diseases like babesiosis and leptospirosis in dogs. Both the diseases show similar clinical manifestations, due to which timely differential diagnosis often gets delayed. The present study focused on diagnosis of major infectious agen...
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| Format: | Article |
| Language: | English |
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Director of Academics and Research, Kerala Veterinary and Animal Sciences University
2023-12-01
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| Series: | Journal of Veterinary and Animal Sciences |
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| Online Access: | https://jvas.in/public_html/upload/article_file/article_file_s6kj9q.pdf?t=s6kj9q |
| _version_ | 1827382972277325824 |
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| author | Asma Idrees P.M. Deepa K. Vinodkumar R. L. Rathish M. Pradeep |
| author_facet | Asma Idrees P.M. Deepa K. Vinodkumar R. L. Rathish M. Pradeep |
| author_sort | Asma Idrees |
| collection | DOAJ |
| description | Acute kidney injury (AKI) is a serious complication of infectious diseases like babesiosis and leptospirosis in dogs. Both the diseases show similar clinical manifestations, due to which timely differential diagnosis often gets delayed. The present study focused on diagnosis of major infectious agents causing AKI and its grading in dogs. Peripheral blood smear examination and PCR were used for the diagnosis of babesiosis. Leptospirosis was screened using PCR and MAT and was later confirmed by MAT on paired sera sample. Diagnosis of AKI was made based on the increase in serum creatinine levels ≥0.3 mg/dL within 48 h of presentation. Staging of animals was carried out as per International Renal Interest Society (IRIS) guidelines. All the dogs with confirmed leptospirosis and 15 per cent of dogs with babesiosis were diagnosed with AKI. The timely diagnosis of AKI in dogs during their initial stages helps to regain normal renal function within short-term treatment itself. |
| first_indexed | 2024-03-08T14:31:12Z |
| format | Article |
| id | doaj.art-9f7de20cec284750b56a7781fbc21c4d |
| institution | Directory Open Access Journal |
| issn | 0971-0701 2582-0605 |
| language | English |
| last_indexed | 2024-03-08T14:31:12Z |
| publishDate | 2023-12-01 |
| publisher | Director of Academics and Research, Kerala Veterinary and Animal Sciences University |
| record_format | Article |
| series | Journal of Veterinary and Animal Sciences |
| spelling | doaj.art-9f7de20cec284750b56a7781fbc21c4d2024-01-12T10:04:11ZengDirector of Academics and Research, Kerala Veterinary and Animal Sciences UniversityJournal of Veterinary and Animal Sciences0971-07012582-06052023-12-0154492192610.51966/jvas.2023.54.4.921-926Assessment of acute kidney injury in dogs suffering from babesiosis and leptospirosisAsma Idrees0https://orcid.org/0009-0007-6839-3452P.M. Deepa1https://orcid.org/0000-0002-0945-3589K. Vinodkumar2https://orcid.org/0000-0001-9643-7976R. L. Rathish3https://orcid.org/0000-0003-2419-4885M. Pradeep4https://orcid.org/0000-0002-5301-7506MVSc Scholar, Department of Veterinary Epidemiology and Preventive Medicine, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, IndiaAssociate Professor & Head, Department of Veterinary Epidemiology and Preventive Medicine, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, IndiaAssistant Professor , Department of Veterinary Epidemiology and Preventive Medicine, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, IndiaAssistant Professor , Department of Veterinary Epidemiology and Preventive Medicine, College of Veterinary and Animal Sciences, Kerala Veterinary and Animal Sciences University, Kerala, IndiaAssistant Professor, Department of Veterinary Pathology, College of Veterinary and Animal Sciences, Kerala Veterinary and Animal Sciences University, Kerala, IndiaAcute kidney injury (AKI) is a serious complication of infectious diseases like babesiosis and leptospirosis in dogs. Both the diseases show similar clinical manifestations, due to which timely differential diagnosis often gets delayed. The present study focused on diagnosis of major infectious agents causing AKI and its grading in dogs. Peripheral blood smear examination and PCR were used for the diagnosis of babesiosis. Leptospirosis was screened using PCR and MAT and was later confirmed by MAT on paired sera sample. Diagnosis of AKI was made based on the increase in serum creatinine levels ≥0.3 mg/dL within 48 h of presentation. Staging of animals was carried out as per International Renal Interest Society (IRIS) guidelines. All the dogs with confirmed leptospirosis and 15 per cent of dogs with babesiosis were diagnosed with AKI. The timely diagnosis of AKI in dogs during their initial stages helps to regain normal renal function within short-term treatment itself.https://jvas.in/public_html/upload/article_file/article_file_s6kj9q.pdf?t=s6kj9qacute kidney injurybabesiosisleptospirosismat |
| spellingShingle | Asma Idrees P.M. Deepa K. Vinodkumar R. L. Rathish M. Pradeep Assessment of acute kidney injury in dogs suffering from babesiosis and leptospirosis Journal of Veterinary and Animal Sciences acute kidney injury babesiosis leptospirosis mat |
| title | Assessment of acute kidney injury in dogs suffering from babesiosis and leptospirosis |
| title_full | Assessment of acute kidney injury in dogs suffering from babesiosis and leptospirosis |
| title_fullStr | Assessment of acute kidney injury in dogs suffering from babesiosis and leptospirosis |
| title_full_unstemmed | Assessment of acute kidney injury in dogs suffering from babesiosis and leptospirosis |
| title_short | Assessment of acute kidney injury in dogs suffering from babesiosis and leptospirosis |
| title_sort | assessment of acute kidney injury in dogs suffering from babesiosis and leptospirosis |
| topic | acute kidney injury babesiosis leptospirosis mat |
| url | https://jvas.in/public_html/upload/article_file/article_file_s6kj9q.pdf?t=s6kj9q |
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