Androgen Reduces Mitochondrial Respiration in Mouse Brown Adipocytes: A Model for Disordered Energy Balance in Polycystic Ovary Syndrome

Androgen Reduces Mitochondrial Respiration in Mouse Brown Adipocytes: A Model for Disordered Energy Balance in Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is a common endocrinopathy that is associated with an adverse metabolic profile including reduced postprandial thermogenesis. Although abnormalities in adipose tissue function have been widely reported in women with PCOS, less is known about direct effects of androge...

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Bibliographic Details
Main Authors: Avi Lerner, Drashti Kewada, Ayan Ahmed, Kate Hardy, Mark Christian, Stephen Franks
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
PCOS
androgens
brown adipose tissue
mitochondrial respiration
UCP1
Online Access:https://www.mdpi.com/1422-0067/22/1/243

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