Computer Simulation of Amperometric Biosensor Response to Mixtures of Compounds

A mathematical model of amperometric biosensors has been developed. The model bases on non-stationary diffusion equations containing a non-linear term related to Michaelis-Menten kinetic of the enzymatic reaction. The model describes the biosensor response to mixtures of multiple compounds in two re...

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Bibliographic Details
Main Authors: R. Baronas, J. Christensen, F. Ivanauskas, J. Kulys
Format: Article
Language:English
Published: Vilnius University Press 2002-12-01
Series:Nonlinear Analysis
Subjects:
Online Access:http://www.zurnalai.vu.lt/nonlinear-analysis/article/view/15190
Description
Summary:A mathematical model of amperometric biosensors has been developed. The model bases on non-stationary diffusion equations containing a non-linear term related to Michaelis-Menten kinetic of the enzymatic reaction. The model describes the biosensor response to mixtures of multiple compounds in two regimes of analysis: batch and flow injection. Using computer simulation, large amount of biosensor response data were synthesised for calibration of a biosensor array to be used for characterization of wastewater. The computer simulation was carried out using the finite difference technique.
ISSN:1392-5113
2335-8963