Persistent T cell-mediated immune responses against Omicron variants after the third COVID-19 mRNA vaccine dose

Persistent T cell-mediated immune responses against Omicron variants after the third COVID-19 mRNA vaccine dose

IntroductionThe prime-boost COVID-19 mRNA vaccination strategy has proven to be effective against severe COVID-19 disease and death. However, concerns have been raised due to decreasing neutralizing antibody levels after COVID-19 vaccination and due to the emergence of new immuno-evasive SARS-CoV-2...

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Main Authors: Milja Belik, Oona Liedes, Saimi Vara, Anu Haveri, Sakari Pöysti, Pekka Kolehmainen, Sari Maljanen, Moona Huttunen, Arttu Reinholm, Rickard Lundberg, Marika Skön, Pamela Österlund, Merit Melin, Arno Hänninen, Antti Hurme, Lauri Ivaska, Paula A. Tähtinen, Johanna Lempainen, Laura Kakkola, Pinja Jalkanen, Ilkka Julkunen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
COVID-19
mRNA vaccines
T cell responses
third vaccine dose
booster vaccine
omicron
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1099246/full

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