p53/<i>TP53</i> Status Assessment in Gastroesophageal Adenocarcinoma

p53/<i>TP53</i> Status Assessment in Gastroesophageal Adenocarcinoma

Chromosomal instability (CIN) is very frequent in gastroesophageal adenocarcinoma (GEA) and it is characterized by <i>TP53</i> deletions/mutations resulting in p53 nuclear accumulation, as revealed by immunohistochemistry (IHC), which considers the cases with “high” staining levels to be...

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Bibliographic Details
Main Authors: Elisa Boldrin, Maria Assunta Piano, Francesco Bernaudo, Rita Alfieri, Maria Raffaella Biasin, Isabella Monia Montagner, Alice Volpato, Genny Mattara, Francesco Lamacchia, Giovanna Magni, Antonio Rosato, Antonio Scapinello, Pierluigi Pilati, Matteo Curtarello
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cancers
Subjects:
p53
<i>TP53</i>
gastroesophageal adenocarcinoma
chromosomal instability (CIN)
liquid biopsy
cell-free DNA (cfDNA)
Online Access:https://www.mdpi.com/2072-6694/15/10/2783

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https://www.mdpi.com/2072-6694/15/10/2783

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