Tissue- and Time-Specific Expression of Otherwise Identical tRNA Genes.

Codon usage bias affects protein translation because tRNAs that recognize synonymous codons differ in their abundance. Although the current dogma states that tRNA expression is exclusively regulated by intrinsic control elements (A- and B-box sequences), we revealed, using a reporter that monitors t...

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Bibliographic Details
Main Authors: Dror Sagi, Roni Rak, Hila Gingold, Idan Adir, Gadi Maayan, Orna Dahan, Limor Broday, Yitzhak Pilpel, Oded Rechavi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4999229?pdf=render