New insights into Regulatory T cells：exosome and non-coding RNA mediated regulation of homeostasis, and resident regulatory T cells
Regulatory T (Treg) cells are a population of cells that are heterogeneous in origin and in functional activity. Treg cells constitute an essential counterbalance to adaptive immune responses. As key regulators of self-tolerance, Treg cells have been implicated in a number of pathologic processes an...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-12-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00574/full |
| _version_ | 1828435254634872832 |
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| author | Peiyao Li Peiyao Li Peiyao Li Changhong Liu Changhong Liu Changhong Liu Zhibin Yu Zhibin Yu Zhibin Yu Minghua Wu Minghua Wu Minghua Wu |
| author_facet | Peiyao Li Peiyao Li Peiyao Li Changhong Liu Changhong Liu Changhong Liu Zhibin Yu Zhibin Yu Zhibin Yu Minghua Wu Minghua Wu Minghua Wu |
| author_sort | Peiyao Li |
| collection | DOAJ |
| description | Regulatory T (Treg) cells are a population of cells that are heterogeneous in origin and in functional activity. Treg cells constitute an essential counterbalance to adaptive immune responses. As key regulators of self-tolerance, Treg cells have been implicated in a number of pathologic processes and considered as therapeutic targets. Here, we summarize recent research regarding Treg cell origins and their functional classification, highlight the role of exosomes and non-coding RNA in modulating Treg cell homeostasis, and discuss the current understanding of resident Treg cells. |
| first_indexed | 2024-12-10T19:04:24Z |
| format | Article |
| id | doaj.art-9f92c8c3068a47509629a698064c44e6 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-12-10T19:04:24Z |
| publishDate | 2016-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-9f92c8c3068a47509629a698064c44e62022-12-22T01:36:56ZengFrontiers Media S.A.Frontiers in Immunology1664-32242016-12-01710.3389/fimmu.2016.00574220329New insights into Regulatory T cells：exosome and non-coding RNA mediated regulation of homeostasis, and resident regulatory T cellsPeiyao Li0Peiyao Li1Peiyao Li2Changhong Liu3Changhong Liu4Changhong Liu5Zhibin Yu6Zhibin Yu7Zhibin Yu8Minghua Wu9Minghua Wu10Minghua Wu11Central South UniversityCentral South UniversityCentral South UniversityCentral South UniversityCentral South UniversityCentral South UniversityCentral South UniversityCentral South UniversityCentral South UniversityCentral South UniversityCentral South UniversityCentral South UniversityRegulatory T (Treg) cells are a population of cells that are heterogeneous in origin and in functional activity. Treg cells constitute an essential counterbalance to adaptive immune responses. As key regulators of self-tolerance, Treg cells have been implicated in a number of pathologic processes and considered as therapeutic targets. Here, we summarize recent research regarding Treg cell origins and their functional classification, highlight the role of exosomes and non-coding RNA in modulating Treg cell homeostasis, and discuss the current understanding of resident Treg cells.http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00574/fullnon-coding RNARegulatory T CellexosomeTreg homeostasisResident Treg cell |
| spellingShingle | Peiyao Li Peiyao Li Peiyao Li Changhong Liu Changhong Liu Changhong Liu Zhibin Yu Zhibin Yu Zhibin Yu Minghua Wu Minghua Wu Minghua Wu New insights into Regulatory T cells：exosome and non-coding RNA mediated regulation of homeostasis, and resident regulatory T cells Frontiers in Immunology non-coding RNA Regulatory T Cell exosome Treg homeostasis Resident Treg cell |
| title | New insights into Regulatory T cells：exosome and non-coding RNA mediated regulation of homeostasis, and resident regulatory T cells |
| title_full | New insights into Regulatory T cells：exosome and non-coding RNA mediated regulation of homeostasis, and resident regulatory T cells |
| title_fullStr | New insights into Regulatory T cells：exosome and non-coding RNA mediated regulation of homeostasis, and resident regulatory T cells |
| title_full_unstemmed | New insights into Regulatory T cells：exosome and non-coding RNA mediated regulation of homeostasis, and resident regulatory T cells |
| title_short | New insights into Regulatory T cells：exosome and non-coding RNA mediated regulation of homeostasis, and resident regulatory T cells |
| title_sort | new insights into regulatory t cells exosome and non coding rna mediated regulation of homeostasis and resident regulatory t cells |
| topic | non-coding RNA Regulatory T Cell exosome Treg homeostasis Resident Treg cell |
| url | http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00574/full |
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