Hypertension linked to Alzheimer’s disease via stroke: Mendelian randomization

Abstract This study aimed to investigate the relationship between hypertension and Alzheimer’s disease (AD) and demonstrate the key role of stroke in this relationship using mediating Mendelian randomization. AD, a neurodegenerative disease characterized by memory loss, cognitive impairment, and beh...

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Bibliographic Details
Main Authors: Chao Tang, Yayu Ma, Xiaoyang Lei, Yaqi Ding, Sushuang Yang, Dian He
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-49087-0