Light’s Criteria Versus Costa’s Criteria in Differentiating Transudative & Exudative Pleural Effusions
Introduction: Aim of this study is to compare COSTA’S and LIGHT’S criteria in identifying exudative from transudative pleural effusions.Materials & Methods: A prospective study that is hospital-based was conducted at GHCCD, during Jan 2017 to August 2018 in 80 patients who presented with pleural...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2023-03-01
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| Series: | Journal of Cardio-Thoracic Medicine |
| Subjects: | |
| Online Access: | https://jctm.mums.ac.ir/article_21901_3a393be1864bb9a079c832659ba9286f.pdf |
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| author | Padmaja Balla Koyyana Preethi Kanakalakshmi K Vishnu Chaitanya |
| author_facet | Padmaja Balla Koyyana Preethi Kanakalakshmi K Vishnu Chaitanya |
| author_sort | Padmaja Balla |
| collection | DOAJ |
| description | Introduction: Aim of this study is to compare COSTA’S and LIGHT’S criteria in identifying exudative from transudative pleural effusions.Materials & Methods: A prospective study that is hospital-based was conducted at GHCCD, during Jan 2017 to August 2018 in 80 patients who presented with pleural effusion. Light’s and Costa’s criteria were applied to differentiate them into transudative and exudative effusions.Results: Among the pleural effusions, 83.75% were exudates and 16.25% were transudates. Tuberculous effusion (45%) was the most common among exudates, and chronic kidney disease (10%) was the most common among the transudates. On biochemical analysis of effusions, the mean pleural fluid cholesterol levels were 74.02±20.51mg/dl and 29.23±7.44mg/dl in exudative and transudative effusions respectively. On ROC analysis, the cut-off value for pleural fluid cholesterol was considered >50mg/dl and <29mg/dl for exudative and transudative effusions respectively. The mean pleural fluid LDH cut-off values on ROC analysis was >231U/L for exudative effusions and <231U/L for transudative effusions. The sensitivity, specificity, PPV, NPV of Lights criteria observed to be 100%, 61.5%, 93.05% & 100% with accuracy of 93.75% whereas the values of Costa’s criteria were 97%, 92%, 98%, 85.7% with accuracy of 96.25% in differentiating exudates and transudates. P-value was statistically significant for both criteria.Conclusion: Pleural fluid LDH and cholesterol are found to be excellent parameters to differentiate transudates and exudates. Costa’s criteria is simple, convenient with almost equal sensitivity and more specificity in comparison to Light’s criteria, with fewer pleural fluid parameters compared to Light’s criteria. |
| first_indexed | 2024-04-09T19:41:16Z |
| format | Article |
| id | doaj.art-9f996d905ef04653b41dcfec986dd6ee |
| institution | Directory Open Access Journal |
| issn | 2345-2447 2322-5750 |
| language | English |
| last_indexed | 2024-04-09T19:41:16Z |
| publishDate | 2023-03-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Journal of Cardio-Thoracic Medicine |
| spelling | doaj.art-9f996d905ef04653b41dcfec986dd6ee2023-04-04T05:52:37ZengMashhad University of Medical SciencesJournal of Cardio-Thoracic Medicine2345-24472322-57502023-03-011111117112310.22038/jctm.2023.70332.140621901Light’s Criteria Versus Costa’s Criteria in Differentiating Transudative & Exudative Pleural EffusionsPadmaja Balla0Koyyana Preethi1Kanakalakshmi K2Vishnu Chaitanya3Department of Pulmonary Medicine, GHCCD, Chinnawaltair, Visakhapatnam, Andhra Pradesh, India.Department of Pulmonary Medicine, GHCCD, Chinnawaltair, Visakhapatnam, Andhra Pradesh, India.Department of Pulmonary Medicine, GHCCD, Chinnawaltair, Visakhapatnam, Andhra Pradesh, India.Department of Pulmonary Medicine, GHCCD, Chinnawaltair, Visakhapatnam, Andhra Pradesh, India.Introduction: Aim of this study is to compare COSTA’S and LIGHT’S criteria in identifying exudative from transudative pleural effusions.Materials & Methods: A prospective study that is hospital-based was conducted at GHCCD, during Jan 2017 to August 2018 in 80 patients who presented with pleural effusion. Light’s and Costa’s criteria were applied to differentiate them into transudative and exudative effusions.Results: Among the pleural effusions, 83.75% were exudates and 16.25% were transudates. Tuberculous effusion (45%) was the most common among exudates, and chronic kidney disease (10%) was the most common among the transudates. On biochemical analysis of effusions, the mean pleural fluid cholesterol levels were 74.02±20.51mg/dl and 29.23±7.44mg/dl in exudative and transudative effusions respectively. On ROC analysis, the cut-off value for pleural fluid cholesterol was considered >50mg/dl and <29mg/dl for exudative and transudative effusions respectively. The mean pleural fluid LDH cut-off values on ROC analysis was >231U/L for exudative effusions and <231U/L for transudative effusions. The sensitivity, specificity, PPV, NPV of Lights criteria observed to be 100%, 61.5%, 93.05% & 100% with accuracy of 93.75% whereas the values of Costa’s criteria were 97%, 92%, 98%, 85.7% with accuracy of 96.25% in differentiating exudates and transudates. P-value was statistically significant for both criteria.Conclusion: Pleural fluid LDH and cholesterol are found to be excellent parameters to differentiate transudates and exudates. Costa’s criteria is simple, convenient with almost equal sensitivity and more specificity in comparison to Light’s criteria, with fewer pleural fluid parameters compared to Light’s criteria.https://jctm.mums.ac.ir/article_21901_3a393be1864bb9a079c832659ba9286f.pdfpleural fluid cholesterolcosta’s criterialight’s criteriapleural fluid ldh |
| spellingShingle | Padmaja Balla Koyyana Preethi Kanakalakshmi K Vishnu Chaitanya Light’s Criteria Versus Costa’s Criteria in Differentiating Transudative & Exudative Pleural Effusions Journal of Cardio-Thoracic Medicine pleural fluid cholesterol costa’s criteria light’s criteria pleural fluid ldh |
| title | Light’s Criteria Versus Costa’s Criteria in Differentiating Transudative & Exudative Pleural Effusions |
| title_full | Light’s Criteria Versus Costa’s Criteria in Differentiating Transudative & Exudative Pleural Effusions |
| title_fullStr | Light’s Criteria Versus Costa’s Criteria in Differentiating Transudative & Exudative Pleural Effusions |
| title_full_unstemmed | Light’s Criteria Versus Costa’s Criteria in Differentiating Transudative & Exudative Pleural Effusions |
| title_short | Light’s Criteria Versus Costa’s Criteria in Differentiating Transudative & Exudative Pleural Effusions |
| title_sort | light s criteria versus costa s criteria in differentiating transudative exudative pleural effusions |
| topic | pleural fluid cholesterol costa’s criteria light’s criteria pleural fluid ldh |
| url | https://jctm.mums.ac.ir/article_21901_3a393be1864bb9a079c832659ba9286f.pdf |
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