The Presence of PDL-1 on CD8+ Lymphocytes Is Linked to Survival in Neonatal Sepsis

The Presence of PDL-1 on CD8+ Lymphocytes Is Linked to Survival in Neonatal Sepsis

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. Neonatal sepsis is the main cause of death in newborns, especially preterm infants. The pathogenesis of sepsis is based on a hyper-inflammatory syndrome combined with an immunosuppressive mechanism in s...

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Bibliographic Details
Main Authors: Lyudmila L. Akhmaltdinova, Zhibek A. Zhumadilova, Svetlana I. Kolesnichenko, Alyona V. Lavrinenko, Irina A. Kadyrova, Olga V. Avdienko, Lyudmila G. Panibratec, Elena V. Vinogradskaya
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Children
Subjects:
neonatal sepsis
neonates
infants
CD8+ T cells
laboratory marker
programmed death receptor
Online Access:https://www.mdpi.com/2227-9067/9/8/1171

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