Primary antiphospholipid syndrome presenting with homonymous quadrantanopsia

Purpose: To report a case of primary antiphospholipid syndrome presenting with isolated homonymous superior quadrantanopsia. Observations: A 50-year-old Korean man presented with subjective visual disturbance for 1 month. Visual field testing showed a right homonymous superior quadrantanopsia. Brain...

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Main Authors: Hee Kyung Yang, Ki Won Moon, Min Jung Ji, Sang Beom Han, Jeong-Min Hwang
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:American Journal of Ophthalmology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993617302475
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author Hee Kyung Yang
Ki Won Moon
Min Jung Ji
Sang Beom Han
Jeong-Min Hwang
author_facet Hee Kyung Yang
Ki Won Moon
Min Jung Ji
Sang Beom Han
Jeong-Min Hwang
author_sort Hee Kyung Yang
collection DOAJ
description Purpose: To report a case of primary antiphospholipid syndrome presenting with isolated homonymous superior quadrantanopsia. Observations: A 50-year-old Korean man presented with subjective visual disturbance for 1 month. Visual field testing showed a right homonymous superior quadrantanopsia. Brain magnetic resonance imaging (MRI) revealed an old infarct in his left occipital lobe and multiple lesions in other areas of the brain. Laboratory tests showed a marked increase in serum anti-β2 glycoprotein I antibody, which remained elevated after 12 weeks. He was diagnosed with primary antiphospholipid syndrome and started anticoagulation therapy. Conclusions and importance: This is the first case report of primary antiphospholipid syndrome presenting with isolated homonymous quadrantanopsia. Antiphospholipid syndrome should be considered as a differential diagnosis in patients with homonymous visual field defects accompanying multiple cerebral infarcts. Keywords: Antiphospholipid syndrome, Visual field defect, Homonymous quadrantanopsia
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spelling doaj.art-9f9c6a4a993b423d815c4c7a474e20232022-12-21T17:45:12ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362018-06-0110208210Primary antiphospholipid syndrome presenting with homonymous quadrantanopsiaHee Kyung Yang0Ki Won Moon1Min Jung Ji2Sang Beom Han3Jeong-Min Hwang4Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South KoreaDepartment of Internal Medicine, Kangwon National University Hospital, Kangwon National University Graduate School of Medicine, Chuncheon, South KoreaDepartment of Ophthalmology, Kangwon National University Hospital, Kangwon National University Graduate School of Medicine, Chuncheon, South KoreaDepartment of Ophthalmology, Kangwon National University Hospital, Kangwon National University Graduate School of Medicine, Chuncheon, South Korea; Corresponding author. Department of Ophthalmology, Kangwon National University Hospital, 156 Baengnyeong-ro, Chuncheon, Kangwon 200-722, South Korea.Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South KoreaPurpose: To report a case of primary antiphospholipid syndrome presenting with isolated homonymous superior quadrantanopsia. Observations: A 50-year-old Korean man presented with subjective visual disturbance for 1 month. Visual field testing showed a right homonymous superior quadrantanopsia. Brain magnetic resonance imaging (MRI) revealed an old infarct in his left occipital lobe and multiple lesions in other areas of the brain. Laboratory tests showed a marked increase in serum anti-β2 glycoprotein I antibody, which remained elevated after 12 weeks. He was diagnosed with primary antiphospholipid syndrome and started anticoagulation therapy. Conclusions and importance: This is the first case report of primary antiphospholipid syndrome presenting with isolated homonymous quadrantanopsia. Antiphospholipid syndrome should be considered as a differential diagnosis in patients with homonymous visual field defects accompanying multiple cerebral infarcts. Keywords: Antiphospholipid syndrome, Visual field defect, Homonymous quadrantanopsiahttp://www.sciencedirect.com/science/article/pii/S2451993617302475
spellingShingle Hee Kyung Yang
Ki Won Moon
Min Jung Ji
Sang Beom Han
Jeong-Min Hwang
Primary antiphospholipid syndrome presenting with homonymous quadrantanopsia
American Journal of Ophthalmology Case Reports
title Primary antiphospholipid syndrome presenting with homonymous quadrantanopsia
title_full Primary antiphospholipid syndrome presenting with homonymous quadrantanopsia
title_fullStr Primary antiphospholipid syndrome presenting with homonymous quadrantanopsia
title_full_unstemmed Primary antiphospholipid syndrome presenting with homonymous quadrantanopsia
title_short Primary antiphospholipid syndrome presenting with homonymous quadrantanopsia
title_sort primary antiphospholipid syndrome presenting with homonymous quadrantanopsia
url http://www.sciencedirect.com/science/article/pii/S2451993617302475
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