Reliable Identification and Interpretation of Single‐Cell Molecular Heterogeneity and Transcriptional Regulation using Dynamic Ensemble Pruning

Abstract Unsupervised clustering is an essential step in identifying cell types from single‐cell RNA sequencing (scRNA‐seq) data. However, a common issue with unsupervised clustering models is that the optimization direction of the objective function and the final generated clustering labels in the...

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Bibliographic Details
Main Authors: Yi Fan, Yunhe Wang, Fuzhou Wang, Lei Huang, Yuning Yang, Ka‐Chun Wong, Xiangtao Li
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202205442