Research Trends on Preventive and Therapeutic Use of TIF4 for Dental Caries and Erosion
Objective: To evaluate TIF4 preventive and therapeutic use in caries and erosive lesions. Material and Methods: Searches were performed in six databases. Studies evaluating TiF4 use in vitro, in situ, and in vivo in caries and erosive lesions were included and imported into VantagePoint™ (VP). Data...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Association of Support to Oral Health Research (APESB)
2023-01-01
|
| Series: | Pesquisa Brasileira em Odontopediatria e Clínica Integrada |
| Subjects: | |
| Online Access: | https://revista.uepb.edu.br/PBOCI/article/view/1673 |
| _version_ | 1797943524635705344 |
|---|---|
| author | Ana Beatriz Chevitarese Karla Lorene de França Leite Guido Artemio Marañón-Vásquez Danielle Masterson José M. Vicente-Gomila Andréa Fonseca Gonçalves Matheus Pitton Lucianne Cople Maia |
| author_facet | Ana Beatriz Chevitarese Karla Lorene de França Leite Guido Artemio Marañón-Vásquez Danielle Masterson José M. Vicente-Gomila Andréa Fonseca Gonçalves Matheus Pitton Lucianne Cople Maia |
| author_sort | Ana Beatriz Chevitarese |
| collection | DOAJ |
| description | Objective: To evaluate TIF4 preventive and therapeutic use in caries and erosive lesions. Material and Methods: Searches were performed in six databases. Studies evaluating TiF4 use in vitro, in situ, and in vivo in caries and erosive lesions were included and imported into VantagePoint™ (VP). Data about publication year, authors, country, journal, study design, outcomes, TIF4 vehicles, application and intervention time, cariogenic challenge, erosive cycles, effects (positive/ negative /null) and approach (preventive/therapeutic) were analyzed through VP and Excel. Results: 93 published studies were included and an increase in publications was observed between 2010 and 2021. Forty-three authors published three or more articles, of which 67.4% were developed in Brazil and published in Caries Research (22.6%). 69.9% were in vitro studies with erosion assays (59.1%) and with preventive approaches (67.4%). The principal vehicle was a solution (69.9%) with a 1-min single application (58.0%) and with an intervention time of 5-7 days (22.6%). The principal cariogenic challenge in vitro was pH cycling (11.8%); in situ was sucrose + biofilm (6.2%); and in vivo, biofilm (6.2%). The most used erosive cycle was 4× per day in in vitro studies (20.4%) and 1× in vivo (2.1%). A positive effect was observed in prevention (41.9%) and treatment (24.7%) studies. Conclusion: TIF4 has shown a positive effect in prevention and therapeutic treatments for dental caries and erosion.
|
| first_indexed | 2024-04-10T20:25:32Z |
| format | Article |
| id | doaj.art-9fa05d3985a647ffb826bae6ded91287 |
| institution | Directory Open Access Journal |
| issn | 1519-0501 1983-4632 |
| language | English |
| last_indexed | 2024-04-10T20:25:32Z |
| publishDate | 2023-01-01 |
| publisher | Association of Support to Oral Health Research (APESB) |
| record_format | Article |
| series | Pesquisa Brasileira em Odontopediatria e Clínica Integrada |
| spelling | doaj.art-9fa05d3985a647ffb826bae6ded912872023-01-25T12:24:14ZengAssociation of Support to Oral Health Research (APESB)Pesquisa Brasileira em Odontopediatria e Clínica Integrada1519-05011983-46322023-01-0122Research Trends on Preventive and Therapeutic Use of TIF4 for Dental Caries and ErosionAna Beatriz ChevitareseKarla Lorene de França LeiteGuido Artemio Marañón-VásquezDanielle MastersonJosé M. Vicente-GomilaAndréa Fonseca GonçalvesMatheus PittonLucianne Cople MaiaObjective: To evaluate TIF4 preventive and therapeutic use in caries and erosive lesions. Material and Methods: Searches were performed in six databases. Studies evaluating TiF4 use in vitro, in situ, and in vivo in caries and erosive lesions were included and imported into VantagePoint™ (VP). Data about publication year, authors, country, journal, study design, outcomes, TIF4 vehicles, application and intervention time, cariogenic challenge, erosive cycles, effects (positive/ negative /null) and approach (preventive/therapeutic) were analyzed through VP and Excel. Results: 93 published studies were included and an increase in publications was observed between 2010 and 2021. Forty-three authors published three or more articles, of which 67.4% were developed in Brazil and published in Caries Research (22.6%). 69.9% were in vitro studies with erosion assays (59.1%) and with preventive approaches (67.4%). The principal vehicle was a solution (69.9%) with a 1-min single application (58.0%) and with an intervention time of 5-7 days (22.6%). The principal cariogenic challenge in vitro was pH cycling (11.8%); in situ was sucrose + biofilm (6.2%); and in vivo, biofilm (6.2%). The most used erosive cycle was 4× per day in in vitro studies (20.4%) and 1× in vivo (2.1%). A positive effect was observed in prevention (41.9%) and treatment (24.7%) studies. Conclusion: TIF4 has shown a positive effect in prevention and therapeutic treatments for dental caries and erosion. https://revista.uepb.edu.br/PBOCI/article/view/1673Dental CariesFluoridesTooth Erosion |
| spellingShingle | Ana Beatriz Chevitarese Karla Lorene de França Leite Guido Artemio Marañón-Vásquez Danielle Masterson José M. Vicente-Gomila Andréa Fonseca Gonçalves Matheus Pitton Lucianne Cople Maia Research Trends on Preventive and Therapeutic Use of TIF4 for Dental Caries and Erosion Pesquisa Brasileira em Odontopediatria e Clínica Integrada Dental Caries Fluorides Tooth Erosion |
| title | Research Trends on Preventive and Therapeutic Use of TIF4 for Dental Caries and Erosion |
| title_full | Research Trends on Preventive and Therapeutic Use of TIF4 for Dental Caries and Erosion |
| title_fullStr | Research Trends on Preventive and Therapeutic Use of TIF4 for Dental Caries and Erosion |
| title_full_unstemmed | Research Trends on Preventive and Therapeutic Use of TIF4 for Dental Caries and Erosion |
| title_short | Research Trends on Preventive and Therapeutic Use of TIF4 for Dental Caries and Erosion |
| title_sort | research trends on preventive and therapeutic use of tif4 for dental caries and erosion |
| topic | Dental Caries Fluorides Tooth Erosion |
| url | https://revista.uepb.edu.br/PBOCI/article/view/1673 |
| work_keys_str_mv | AT anabeatrizchevitarese researchtrendsonpreventiveandtherapeuticuseoftif4fordentalcariesanderosion AT karlalorenedefrancaleite researchtrendsonpreventiveandtherapeuticuseoftif4fordentalcariesanderosion AT guidoartemiomaranonvasquez researchtrendsonpreventiveandtherapeuticuseoftif4fordentalcariesanderosion AT daniellemasterson researchtrendsonpreventiveandtherapeuticuseoftif4fordentalcariesanderosion AT josemvicentegomila researchtrendsonpreventiveandtherapeuticuseoftif4fordentalcariesanderosion AT andreafonsecagoncalves researchtrendsonpreventiveandtherapeuticuseoftif4fordentalcariesanderosion AT matheuspitton researchtrendsonpreventiveandtherapeuticuseoftif4fordentalcariesanderosion AT luciannecoplemaia researchtrendsonpreventiveandtherapeuticuseoftif4fordentalcariesanderosion |