Specialized acyl carrier protein used by serine palmitoyltransferase to synthesize sphingolipids in Rhodobacteria

Specialized acyl carrier protein used by serine palmitoyltransferase to synthesize sphingolipids in Rhodobacteria

Serine palmitoyltransferase (SPT) catalyzes the first and committed step in sphingolipid biosynthesis condensating L-serine and acyl-CoA to form 3-oxo-sphinganine. Whenever the structural gene for SPT is present in genomes of Rhodobacteria (α-, β-, and γ-Proteobacteria), it co-occurs with genes codi...

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Bibliographic Details
Main Authors: Jonathan Padilla-Gómez, Roberto Jhonatan Olea-Ozuna, Sandra Contreras-Martínez, Orlando Morales-Tarré, Daniela A. García-Soriano, Diana X. Sahonero-Canavesi, Sebastian Poggio, Sergio Encarnación-Guevara, Isabel M. López-Lara, Otto Geiger
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Microbiology
Subjects:
ACP
acyl-ACP synthetase
fatty acid metabolism
serine palmitoyltransferase
3-oxo-sphinganine
sphingolipid
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.961041/full

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