HETEROTOPIC TRANSPLANTATION OF HEART AND THE REGULATORY MECHANISMS OF THE ADAPTATION
Aim. The article describes the results of an experimental study of the adaptation mechanisms of heart and transplant (cardio-pulmonary complex, CPC) in heterotopic transplantation.Materials and methods. CPC`s from recipients (8 dogs) were transplanted in left oblique-diaphragmatic sinus of donor`s (...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2016-06-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/594 |
| _version_ | 1797872915142672384 |
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| author | A. N. Baikov V. E. Tolpekin M. A. Medvedev E. V. Semichiev S. D. Ivanov |
| author_facet | A. N. Baikov V. E. Tolpekin M. A. Medvedev E. V. Semichiev S. D. Ivanov |
| author_sort | A. N. Baikov |
| collection | DOAJ |
| description | Aim. The article describes the results of an experimental study of the adaptation mechanisms of heart and transplant (cardio-pulmonary complex, CPC) in heterotopic transplantation.Materials and methods. CPC`s from recipients (8 dogs) were transplanted in left oblique-diaphragmatic sinus of donor`s (8 dogs). As a results of parallel connection transplant pre- and post-load of donor`s heart was reduces. Oxygenated blood by CPC was passed the left chambers of donor`s heart and returned to the aorta. Another part from pulmonary artery shunted to the right chamber of CPC as a result decreased systolic pressure on the right ventricle of heart. During the co-working of CPC and heart was happened synchronization.Consequently self-regulating process of circulatory system provides mechanism of adaptation in new conditions. The findings are important for understanding the effectiveness and relevance of this bilogical method of circulatory support. |
| first_indexed | 2024-04-10T01:07:45Z |
| format | Article |
| id | doaj.art-9fa651405bbb42b5a316977890d32f97 |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:07:45Z |
| publishDate | 2016-06-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-9fa651405bbb42b5a316977890d32f972023-03-13T09:58:22ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842016-06-011535910.20538/1682-0363-2016-3-5-9539HETEROTOPIC TRANSPLANTATION OF HEART AND THE REGULATORY MECHANISMS OF THE ADAPTATIONA. N. Baikov0V. E. Tolpekin1M. A. Medvedev2E. V. Semichiev3S. D. Ivanov4Сибирский государственный медицинский университет, г. ТомскФедеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова, г. МоскваСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскAim. The article describes the results of an experimental study of the adaptation mechanisms of heart and transplant (cardio-pulmonary complex, CPC) in heterotopic transplantation.Materials and methods. CPC`s from recipients (8 dogs) were transplanted in left oblique-diaphragmatic sinus of donor`s (8 dogs). As a results of parallel connection transplant pre- and post-load of donor`s heart was reduces. Oxygenated blood by CPC was passed the left chambers of donor`s heart and returned to the aorta. Another part from pulmonary artery shunted to the right chamber of CPC as a result decreased systolic pressure on the right ventricle of heart. During the co-working of CPC and heart was happened synchronization.Consequently self-regulating process of circulatory system provides mechanism of adaptation in new conditions. The findings are important for understanding the effectiveness and relevance of this bilogical method of circulatory support.https://bulletin.ssmu.ru/jour/article/view/594гетеротопическая трансплантациявспомогательное кровообращениеадаптация сердца |
| spellingShingle | A. N. Baikov V. E. Tolpekin M. A. Medvedev E. V. Semichiev S. D. Ivanov HETEROTOPIC TRANSPLANTATION OF HEART AND THE REGULATORY MECHANISMS OF THE ADAPTATION Бюллетень сибирской медицины гетеротопическая трансплантация вспомогательное кровообращение адаптация сердца |
| title | HETEROTOPIC TRANSPLANTATION OF HEART AND THE REGULATORY MECHANISMS OF THE ADAPTATION |
| title_full | HETEROTOPIC TRANSPLANTATION OF HEART AND THE REGULATORY MECHANISMS OF THE ADAPTATION |
| title_fullStr | HETEROTOPIC TRANSPLANTATION OF HEART AND THE REGULATORY MECHANISMS OF THE ADAPTATION |
| title_full_unstemmed | HETEROTOPIC TRANSPLANTATION OF HEART AND THE REGULATORY MECHANISMS OF THE ADAPTATION |
| title_short | HETEROTOPIC TRANSPLANTATION OF HEART AND THE REGULATORY MECHANISMS OF THE ADAPTATION |
| title_sort | heterotopic transplantation of heart and the regulatory mechanisms of the adaptation |
| topic | гетеротопическая трансплантация вспомогательное кровообращение адаптация сердца |
| url | https://bulletin.ssmu.ru/jour/article/view/594 |
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