Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresis

Platelet aggregation was studied in a patient with familial hypercholesterolemia immediately after aphereis selective for low-density lipoprotein (LDL), a lipid-lowering procedure.This treatment reduced plasmatic levels of total and LDL-cholesterol, apo B, and triglyceride. Increased platelet aggreg...

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প্রধান লেখক: Madalena Nunes da Silva Pares, Elbio Antonio D'Amico, José Mauro Kutner, Dalton de Alencar Fischer Chamone, Sergio Paulo Bydlowski
বিন্যাস: প্রবন্ধ
ভাষা:English
প্রকাশিত: Associação Paulista de Medicina
মালা:São Paulo Medical Journal
বিষয়গুলি:
অনলাইন ব্যবহার করুন:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801997000300009&lng=en&tlng=en
বিবরন
সংক্ষিপ্ত:Platelet aggregation was studied in a patient with familial hypercholesterolemia immediately after aphereis selective for low-density lipoprotein (LDL), a lipid-lowering procedure.This treatment reduced plasmatic levels of total and LDL-cholesterol, apo B, and triglyceride. Increased platelet aggregation was reduced immediately after the apheresis in whole blood as well as in platelet-rich plasma. However, aggregation in washed platelets remained unchanged after LDL-apheresis. In conclusion, in this patient reduction of LDL-cholesterol improved platelet function in the very short term.
আইএসএসএন:1806-9460