Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresis
Platelet aggregation was studied in a patient with familial hypercholesterolemia immediately after aphereis selective for low-density lipoprotein (LDL), a lipid-lowering procedure.This treatment reduced plasmatic levels of total and LDL-cholesterol, apo B, and triglyceride. Increased platelet aggreg...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Associação Paulista de Medicina
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| Series: | São Paulo Medical Journal |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801997000300009&lng=en&tlng=en |
| _version_ | 1818158531314974720 |
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| author | Madalena Nunes da Silva Pares Elbio Antonio D'Amico José Mauro Kutner Dalton de Alencar Fischer Chamone Sergio Paulo Bydlowski |
| author_facet | Madalena Nunes da Silva Pares Elbio Antonio D'Amico José Mauro Kutner Dalton de Alencar Fischer Chamone Sergio Paulo Bydlowski |
| author_sort | Madalena Nunes da Silva Pares |
| collection | DOAJ |
| description | Platelet aggregation was studied in a patient with familial hypercholesterolemia immediately after aphereis selective for low-density lipoprotein (LDL), a lipid-lowering procedure.This treatment reduced plasmatic levels of total and LDL-cholesterol, apo B, and triglyceride. Increased platelet aggregation was reduced immediately after the apheresis in whole blood as well as in platelet-rich plasma. However, aggregation in washed platelets remained unchanged after LDL-apheresis. In conclusion, in this patient reduction of LDL-cholesterol improved platelet function in the very short term. |
| first_indexed | 2024-12-11T15:31:34Z |
| format | Article |
| id | doaj.art-9fa86a7d24e44a43a73f6b494505035c |
| institution | Directory Open Access Journal |
| issn | 1806-9460 |
| language | English |
| last_indexed | 2024-12-11T15:31:34Z |
| publisher | Associação Paulista de Medicina |
| record_format | Article |
| series | São Paulo Medical Journal |
| spelling | doaj.art-9fa86a7d24e44a43a73f6b494505035c2022-12-22T01:00:03ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-946011531448145110.1590/S1516-31801997000300009S1516-31801997000300009Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresisMadalena Nunes da Silva Pares0Elbio Antonio D'Amico1José Mauro Kutner2Dalton de Alencar Fischer Chamone3Sergio Paulo Bydlowski4Fundação Pró-Sangue Hemocentro de São PauloFundação Pró-Sangue Hemocentro de São PauloFundação Pró-Sangue Hemocentro de São PauloFundação Pró-Sangue Hemocentro de São PauloFundação Pró-Sangue Hemocentro de São PauloPlatelet aggregation was studied in a patient with familial hypercholesterolemia immediately after aphereis selective for low-density lipoprotein (LDL), a lipid-lowering procedure.This treatment reduced plasmatic levels of total and LDL-cholesterol, apo B, and triglyceride. Increased platelet aggregation was reduced immediately after the apheresis in whole blood as well as in platelet-rich plasma. However, aggregation in washed platelets remained unchanged after LDL-apheresis. In conclusion, in this patient reduction of LDL-cholesterol improved platelet function in the very short term.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801997000300009&lng=en&tlng=enPlatelet aggregationFamilial hypercholesterolemiaLDL-apheresis |
| spellingShingle | Madalena Nunes da Silva Pares Elbio Antonio D'Amico José Mauro Kutner Dalton de Alencar Fischer Chamone Sergio Paulo Bydlowski Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresis São Paulo Medical Journal Platelet aggregation Familial hypercholesterolemia LDL-apheresis |
| title | Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresis |
| title_full | Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresis |
| title_fullStr | Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresis |
| title_full_unstemmed | Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresis |
| title_short | Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresis |
| title_sort | platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective ldl apheresis |
| topic | Platelet aggregation Familial hypercholesterolemia LDL-apheresis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801997000300009&lng=en&tlng=en |
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