Integrative Multi-Omics Approach in Vascular Ehlers–Danlos Syndrome: Further Insights into the Disease Mechanisms by Proteomic Analysis of Patient Dermal Fibroblasts
<b>Background</b>: Dominant mutations in <i>COL3A1</i> are known to cause vascular Ehlers–Danlos syndrome (vEDS) by impairing extracellular matrix (ECM) homeostasis. This disruption leads to the fragility of soft connective tissues and a significantly increased risk of life-t...
मुख्य लेखकों: | , , , , , , , , , |
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स्वरूप: | लेख |
भाषा: | English |
प्रकाशित: |
MDPI AG
2024-11-01
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श्रृंखला: | Biomedicines |
विषय: | |
ऑनलाइन पहुंच: | https://www.mdpi.com/2227-9059/12/12/2749 |