Reiterating the role of corpus callosum in generalization of interictal and ictal epileptiform discharges: a case report with post-callosotomy intracranial electroencephalography in Lennox–Gastaut syndrome
Lennox–Gastaut syndrome (LGS) is an epileptic encephalopathy characterized by delayed mental development and intractable multiple seizure types, predominantly tonic. Drop attacks are the commonest and the most disabling type of seizures. Resective surgery is often not possible in LGS as the electroe...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2021-10-01
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| Series: | Эпилепсия и пароксизмальные состояния |
| Subjects: | |
| Online Access: | https://www.epilepsia.su/jour/article/view/729 |
| _version_ | 1797879396473765888 |
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| author | S. Gopinath A. Pillai A. G. Diwan J. V. Pattisapu K. Radhakrishnan |
| author_facet | S. Gopinath A. Pillai A. G. Diwan J. V. Pattisapu K. Radhakrishnan |
| author_sort | S. Gopinath |
| collection | DOAJ |
| description | Lennox–Gastaut syndrome (LGS) is an epileptic encephalopathy characterized by delayed mental development and intractable multiple seizure types, predominantly tonic. Drop attacks are the commonest and the most disabling type of seizures. Resective surgery is often not possible in LGS as the electroencephalogram (EEG) abnormalities are usually multifocal and generalized, and magnetic resonance image is often either normal or multilesional. We report a case of LGS with bilateral parieto-occipital gliosis where EEG before and after callosotomy demonstrated synchronized bilateral interictal epileptiform discharges and ictal discharges becoming desynchronized and running down. This phenomenon emphasizes the role of the corpus callosum in secondary bilateral synchrony. |
| first_indexed | 2024-04-10T02:46:56Z |
| format | Article |
| id | doaj.art-9fab1818d2f346f3b968002de5b682a6 |
| institution | Directory Open Access Journal |
| issn | 2077-8333 2311-4088 |
| language | Russian |
| last_indexed | 2024-04-10T02:46:56Z |
| publishDate | 2021-10-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Эпилепсия и пароксизмальные состояния |
| spelling | doaj.art-9fab1818d2f346f3b968002de5b682a62023-03-13T07:44:18ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882021-10-0113324925310.17749/2077-8333/epi.par.con.2021.086549Reiterating the role of corpus callosum in generalization of interictal and ictal epileptiform discharges: a case report with post-callosotomy intracranial electroencephalography in Lennox–Gastaut syndromeS. Gopinath0A. Pillai1A. G. Diwan2J. V. Pattisapu3K. Radhakrishnan4Amrita Advanced Centre for Epilepsy, Amrita Institute of Medical ScienceAmrita Advanced Centre for Epilepsy, Amrita Institute of Medical ScienceNarayani HospitalUniversity of Central Florida College of Medicine; Arnold Palmer Hospital for ChildrenAmrita Advanced Centre for Epilepsy, Amrita Institute of Medical ScienceLennox–Gastaut syndrome (LGS) is an epileptic encephalopathy characterized by delayed mental development and intractable multiple seizure types, predominantly tonic. Drop attacks are the commonest and the most disabling type of seizures. Resective surgery is often not possible in LGS as the electroencephalogram (EEG) abnormalities are usually multifocal and generalized, and magnetic resonance image is often either normal or multilesional. We report a case of LGS with bilateral parieto-occipital gliosis where EEG before and after callosotomy demonstrated synchronized bilateral interictal epileptiform discharges and ictal discharges becoming desynchronized and running down. This phenomenon emphasizes the role of the corpus callosum in secondary bilateral synchrony.https://www.epilepsia.su/jour/article/view/729epileptic encephalopathylennox–gastaut syndromecorpus callosumcallosotomy |
| spellingShingle | S. Gopinath A. Pillai A. G. Diwan J. V. Pattisapu K. Radhakrishnan Reiterating the role of corpus callosum in generalization of interictal and ictal epileptiform discharges: a case report with post-callosotomy intracranial electroencephalography in Lennox–Gastaut syndrome Эпилепсия и пароксизмальные состояния epileptic encephalopathy lennox–gastaut syndrome corpus callosum callosotomy |
| title | Reiterating the role of corpus callosum in generalization of interictal and ictal epileptiform discharges: a case report with post-callosotomy intracranial electroencephalography in Lennox–Gastaut syndrome |
| title_full | Reiterating the role of corpus callosum in generalization of interictal and ictal epileptiform discharges: a case report with post-callosotomy intracranial electroencephalography in Lennox–Gastaut syndrome |
| title_fullStr | Reiterating the role of corpus callosum in generalization of interictal and ictal epileptiform discharges: a case report with post-callosotomy intracranial electroencephalography in Lennox–Gastaut syndrome |
| title_full_unstemmed | Reiterating the role of corpus callosum in generalization of interictal and ictal epileptiform discharges: a case report with post-callosotomy intracranial electroencephalography in Lennox–Gastaut syndrome |
| title_short | Reiterating the role of corpus callosum in generalization of interictal and ictal epileptiform discharges: a case report with post-callosotomy intracranial electroencephalography in Lennox–Gastaut syndrome |
| title_sort | reiterating the role of corpus callosum in generalization of interictal and ictal epileptiform discharges a case report with post callosotomy intracranial electroencephalography in lennox gastaut syndrome |
| topic | epileptic encephalopathy lennox–gastaut syndrome corpus callosum callosotomy |
| url | https://www.epilepsia.su/jour/article/view/729 |
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