Central line-associated bloodstream infection in pediatric oncology patients in Qatar: A prospective study
Objective: To assess the central line-associated bloodstream infection (CLABSI) rate and risk factors in hospitalized pediatric oncology patients in Qatar. Materials and Methods: A prospective, observational study was conducted in pediatric oncology department at Hamad Medical Corporation, Qatar bet...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Journal of Applied Hematology |
| Subjects: | |
| Online Access: | http://www.jahjournal.org/article.asp?issn=1658-5127;year=2017;volume=8;issue=2;spage=49;epage=53;aulast=Alsaad |
| _version_ | 1818892097178042368 |
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| author | Tayseer Alsaad Mohamad Qaisuddin Doua AlSaad Prem Chandra Omar AlAbd Abdulla A Nasser Mohamad Janahi Anu Pilari Hisham Morsi |
| author_facet | Tayseer Alsaad Mohamad Qaisuddin Doua AlSaad Prem Chandra Omar AlAbd Abdulla A Nasser Mohamad Janahi Anu Pilari Hisham Morsi |
| author_sort | Tayseer Alsaad |
| collection | DOAJ |
| description | Objective: To assess the central line-associated bloodstream infection (CLABSI) rate and risk factors in hospitalized pediatric oncology patients in Qatar.
Materials and Methods: A prospective, observational study was conducted in pediatric oncology department at Hamad Medical Corporation, Qatar between January 1, 2013 and December 31, 2014. All children <14 years of age with malignancy who required a central line catheter were included.
Results: Thirty-seven subcutaneous tunneled catheters were inserted. Majority of the patients were younger than 10 years of age (88%), and the male-to-female ratio was 1.3:1. Leukemia was the most frequently encountered diagnosis. The overall mean central venous catheter (CVC) infection rate was 4.12 CLABSI per 1000 CVC days (95% confidence interval 2.41, 7.05). Thirteen catheters were infected (35.1%), of which 11 catheters were Porta-a-Cath, and two catheters were Hickman double lumen line. Gram-negative bacteria were found in 69.2% of the CLABSI cases, and no fungal infection was detected. Gender, age, type of disease, and type of catheter were not associated with increased risk for CLABSI (P > 0.05). The mean number of days with neutropenia was more in the patients who had CLABSI 73.5 ± 44.5 compared to the patients who did not have CLABSI 48.9 ± 52.1, but the difference did not reach statistical significance (P = 0.140).
Conclusion: The incidence rate of CLABSI continues to be a concern in hospitalized pediatric oncology patients in Qatar. This study showed that mean CVC infection rate was 4.12 CLABSI per 1000 CVC days. Gram-negative bacteria CLABSI were the dominant organism in this group of patients and catheters. |
| first_indexed | 2024-12-19T17:51:17Z |
| format | Article |
| id | doaj.art-9fad6790ea044f2c9358792cd8c281f2 |
| institution | Directory Open Access Journal |
| issn | 1658-5127 |
| language | English |
| last_indexed | 2024-12-19T17:51:17Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Applied Hematology |
| spelling | doaj.art-9fad6790ea044f2c9358792cd8c281f22022-12-21T20:11:55ZengWolters Kluwer Medknow PublicationsJournal of Applied Hematology1658-51272017-01-0182495310.4103/joah.joah_13_17Central line-associated bloodstream infection in pediatric oncology patients in Qatar: A prospective studyTayseer AlsaadMohamad QaisuddinDoua AlSaadPrem ChandraOmar AlAbdAbdulla A NasserMohamad JanahiAnu PilariHisham MorsiObjective: To assess the central line-associated bloodstream infection (CLABSI) rate and risk factors in hospitalized pediatric oncology patients in Qatar. Materials and Methods: A prospective, observational study was conducted in pediatric oncology department at Hamad Medical Corporation, Qatar between January 1, 2013 and December 31, 2014. All children <14 years of age with malignancy who required a central line catheter were included. Results: Thirty-seven subcutaneous tunneled catheters were inserted. Majority of the patients were younger than 10 years of age (88%), and the male-to-female ratio was 1.3:1. Leukemia was the most frequently encountered diagnosis. The overall mean central venous catheter (CVC) infection rate was 4.12 CLABSI per 1000 CVC days (95% confidence interval 2.41, 7.05). Thirteen catheters were infected (35.1%), of which 11 catheters were Porta-a-Cath, and two catheters were Hickman double lumen line. Gram-negative bacteria were found in 69.2% of the CLABSI cases, and no fungal infection was detected. Gender, age, type of disease, and type of catheter were not associated with increased risk for CLABSI (P > 0.05). The mean number of days with neutropenia was more in the patients who had CLABSI 73.5 ± 44.5 compared to the patients who did not have CLABSI 48.9 ± 52.1, but the difference did not reach statistical significance (P = 0.140). Conclusion: The incidence rate of CLABSI continues to be a concern in hospitalized pediatric oncology patients in Qatar. This study showed that mean CVC infection rate was 4.12 CLABSI per 1000 CVC days. Gram-negative bacteria CLABSI were the dominant organism in this group of patients and catheters.http://www.jahjournal.org/article.asp?issn=1658-5127;year=2017;volume=8;issue=2;spage=49;epage=53;aulast=AlsaadBloodstream infectioncentral catheterCLABSIpediatric oncology |
| spellingShingle | Tayseer Alsaad Mohamad Qaisuddin Doua AlSaad Prem Chandra Omar AlAbd Abdulla A Nasser Mohamad Janahi Anu Pilari Hisham Morsi Central line-associated bloodstream infection in pediatric oncology patients in Qatar: A prospective study Journal of Applied Hematology Bloodstream infection central catheter CLABSI pediatric oncology |
| title | Central line-associated bloodstream infection in pediatric oncology patients in Qatar: A prospective study |
| title_full | Central line-associated bloodstream infection in pediatric oncology patients in Qatar: A prospective study |
| title_fullStr | Central line-associated bloodstream infection in pediatric oncology patients in Qatar: A prospective study |
| title_full_unstemmed | Central line-associated bloodstream infection in pediatric oncology patients in Qatar: A prospective study |
| title_short | Central line-associated bloodstream infection in pediatric oncology patients in Qatar: A prospective study |
| title_sort | central line associated bloodstream infection in pediatric oncology patients in qatar a prospective study |
| topic | Bloodstream infection central catheter CLABSI pediatric oncology |
| url | http://www.jahjournal.org/article.asp?issn=1658-5127;year=2017;volume=8;issue=2;spage=49;epage=53;aulast=Alsaad |
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