Association of fertility diet score with endometriosis: a case–control study
Background and aimsDifferent factors, such as environmental, epigenetic, genetic and immunological, have been identified as potential risks for developing endometriosis. However, the correlation between dietary patterns and endometriosis is currently unknown. The aim of this study was to explore the...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2023.1222018/full |
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| author | Sakine Ghasemisedaghat Ghazaleh Eslamian Seyyedeh Neda Kazemi Bahram Rashidkhani Robabeh Taheripanah |
| author_facet | Sakine Ghasemisedaghat Ghazaleh Eslamian Seyyedeh Neda Kazemi Bahram Rashidkhani Robabeh Taheripanah |
| author_sort | Sakine Ghasemisedaghat |
| collection | DOAJ |
| description | Background and aimsDifferent factors, such as environmental, epigenetic, genetic and immunological, have been identified as potential risks for developing endometriosis. However, the correlation between dietary patterns and endometriosis is currently unknown. The aim of this study was to explore the potential link between fertility diet score and the odds of endometriosis.MethodsThis study was a hospital-based case–control study that took place in a gynecology clinic in Tehran, Iran, between February 2021 and January 2022. A total of 107 newly diagnosed endometriosis cases and 210 controls were included. The participants' habitual diets were evaluated using a food frequency questionnaire, and their fertility diet score was estimated using a point system based on Chavarro et al.'s criteria. The logistic regression was utilized to calculate the odds ratios (OR) with 95% confidence intervals (CIs).ResultsThe study found that women who adherence to fertility diet have a lower odds of endometriosis. This was observed in both the base model and the adjusted model, with a significant decrease in odds of endometriosis by 66% (OR = 0.44, 95%CI = 0.27–0.71, p = 0.001) and 54% (aOR = 0.46, 95%CI = 0.23–0.90, p = 0.022), respectively. Additionally, consuming vegetable proteins and multivitamins were also associated with lower odds of endometriosis. On the other hand, consuming animal proteins, heme iron, and having a high glycemic load were associated with significantly higher odds of endometriosis.ConclusionOur research supports the hypothesis that following a fertility diet may decrease the odds of endometriosis in Iranian women. However, these findings should be verified through extensive, prospective studies. |
| first_indexed | 2024-03-12T11:26:19Z |
| format | Article |
| id | doaj.art-9fb13cc09bcf4ec29ed750b57e875253 |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-03-12T11:26:19Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-9fb13cc09bcf4ec29ed750b57e8752532023-09-01T08:31:43ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2023-09-011010.3389/fnut.2023.12220181222018Association of fertility diet score with endometriosis: a case–control studySakine Ghasemisedaghat0Ghazaleh Eslamian1Seyyedeh Neda Kazemi2Bahram Rashidkhani3Robabeh Taheripanah4Department of Cellular and Molecular Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Cellular and Molecular Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Obstetrics and Gynecology, School of Medicine, Preventative Gynecology Research Center, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Community Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Obstetrics and Gynecology, School of Medicine, Men's Health and Reproductive Health Research Center, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranBackground and aimsDifferent factors, such as environmental, epigenetic, genetic and immunological, have been identified as potential risks for developing endometriosis. However, the correlation between dietary patterns and endometriosis is currently unknown. The aim of this study was to explore the potential link between fertility diet score and the odds of endometriosis.MethodsThis study was a hospital-based case–control study that took place in a gynecology clinic in Tehran, Iran, between February 2021 and January 2022. A total of 107 newly diagnosed endometriosis cases and 210 controls were included. The participants' habitual diets were evaluated using a food frequency questionnaire, and their fertility diet score was estimated using a point system based on Chavarro et al.'s criteria. The logistic regression was utilized to calculate the odds ratios (OR) with 95% confidence intervals (CIs).ResultsThe study found that women who adherence to fertility diet have a lower odds of endometriosis. This was observed in both the base model and the adjusted model, with a significant decrease in odds of endometriosis by 66% (OR = 0.44, 95%CI = 0.27–0.71, p = 0.001) and 54% (aOR = 0.46, 95%CI = 0.23–0.90, p = 0.022), respectively. Additionally, consuming vegetable proteins and multivitamins were also associated with lower odds of endometriosis. On the other hand, consuming animal proteins, heme iron, and having a high glycemic load were associated with significantly higher odds of endometriosis.ConclusionOur research supports the hypothesis that following a fertility diet may decrease the odds of endometriosis in Iranian women. However, these findings should be verified through extensive, prospective studies.https://www.frontiersin.org/articles/10.3389/fnut.2023.1222018/fullfertility diet scoredietary assessmentendometriosiswomencase-control |
| spellingShingle | Sakine Ghasemisedaghat Ghazaleh Eslamian Seyyedeh Neda Kazemi Bahram Rashidkhani Robabeh Taheripanah Association of fertility diet score with endometriosis: a case–control study Frontiers in Nutrition fertility diet score dietary assessment endometriosis women case-control |
| title | Association of fertility diet score with endometriosis: a case–control study |
| title_full | Association of fertility diet score with endometriosis: a case–control study |
| title_fullStr | Association of fertility diet score with endometriosis: a case–control study |
| title_full_unstemmed | Association of fertility diet score with endometriosis: a case–control study |
| title_short | Association of fertility diet score with endometriosis: a case–control study |
| title_sort | association of fertility diet score with endometriosis a case control study |
| topic | fertility diet score dietary assessment endometriosis women case-control |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2023.1222018/full |
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