Prognostic significance of overexpressed p16INK4a in patients with cervical cancer: a meta-analysis.
BACKGROUND: p16INK4a is a tumor suppressor protein which is induced in cells upon the interaction of high-risk HPV E7 with the retinoblastoma protein by a positive feedback loop, but cannot exert its suppressing effect. Previous reports suggested that p16INK4a immunostaining allows precise identific...
Main Authors: | Jiaying Lin, Andreas E Albers, Jinbao Qin, Andreas M Kaufmann |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4154680?pdf=render |
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