Elevation of artemisinin content by co-transformation of artemisinin biosynthetic pathway genes and trichome-specific transcription factors in Artemisia annua

Elevation of artemisinin content by co-transformation of artemisinin biosynthetic pathway genes and trichome-specific transcription factors in Artemisia annua

Artemisinin, derived from Artemisia annua, is currently used as the first-line treatment for malaria. However, wild-type plants have a low artemisinin biosynthesis rate. Although yeast engineering and plant synthetic biology have shown promising results, plant genetic engineering is considered the m...

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Bibliographic Details
Main Authors: Danial Hassani, Ayat Taheri, Xueqing Fu, Wei Qin, Liu Hang, Yanan Ma, Kexuan Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Plant Science
Subjects:
artemisinin
co-expression
transcription factor
transformation
metabolic engineering
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2023.1118082/full

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